InAADR

Protein Information

Protein Name: CYP2B protein (Q14097)
Gene Name: CYP2B
Description: CYP2B protein (CYP2B7P1 protein)
PDB ID:
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Ethinyl Estradiol Hepatotoxicity PXR is involved in the induction of CYP3A23 by pharmacologically and structurally distinct steroids and xenobiotics Moreover@ PXR-mediated PCB activation of the (CYP3A23)2-tk-CAT may serve as a rapid assay for effects of nonplanar PCBs [ ADR Type 2 ] Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database