| Protein Name: | TNF receptor-associated factor 1 (Q13077) |
|---|---|
| Gene Name: | TRAF1 |
| Description: | TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6) |
| PDB ID: | 3M0D |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Bryostatin 1 | Apoptosis | Paclitaxel-induced apoptosis of breast cancer cells Expression of the anti-apoptotic tumor necrosis factor receptor associated factor 1 (TRAF1) and defender-against cell death (DAD-1) is regulated by NF-kappaB in certain breast cancer cells [ ADR Type 2 ] | Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor |
| Paclitaxel | Apoptosis Of Breast Cancer Cells | Expression of the anti-apoptotic tumor necrosis factor receptor associated factor 1 (TRAF1) and defender-against cell death (DAD-1) is regulated by NF-kappaB in certain breast cancer cells@which increases paclitaxel-induced apoptosis of breast cancer cells. [ ADR Type 2 ] | Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor |
This panel provides information on drug category
| Toxicity | Source |
|---|