InAADR

Protein Information

Protein Name: Prostaglandin G/H synthase 2 precursor (Q05769)
Gene Name: Ptgs2
Description:
PDB ID: 1CVU
Protein Family: PF03098, PS50026
Protein Category: Enzyme

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain Large-scale prediction and testing of drug activity on side-effect targets
Aplastic Anaemia Large-scale prediction and testing of drug activity on side-effect targets
Colitis Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors
Dyspepsia Large-scale prediction and testing of drug activity on side-effect targets
Edema Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice
Erythema Multiforme Large-scale prediction and testing of drug activity on side-effect targets
Flatulence Large-scale prediction and testing of drug activity on side-effect targets
Gastric Ulcer Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats
Gastrointestinal Haemorrhage Large-scale prediction and testing of drug activity on side-effect targets
Haematuria Large-scale prediction and testing of drug activity on side-effect targets
Haemorrhagic Diathesis Large-scale prediction and testing of drug activity on side-effect targets
Hepatitis Large-scale prediction and testing of drug activity on side-effect targets
Nephropathy Large-scale prediction and testing of drug activity on side-effect targets
Oedema Large-scale prediction and testing of drug activity on side-effect targets
Oliguria Large-scale prediction and testing of drug activity on side-effect targets
Peptic Ulcer Large-scale prediction and testing of drug activity on side-effect targets
Pruritus Large-scale prediction and testing of drug activity on side-effect targets
Renal Failure Large-scale prediction and testing of drug activity on side-effect targets
Thrombocytopenia Large-scale prediction and testing of drug activity on side-effect targets
Tinnitus Large-scale prediction and testing of drug activity on side-effect targets
Ulceration COX-2 inhibition, H. pylori infection and the risk of gastrointestinal complications

InAADR: Drug-Protein-ADRs database