| Protein Name: | Focal adhesion kinase (FAK) (Q05397) |
|---|---|
| Gene Name: | PTK2 |
| Description: | |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Mannitol | Apoptosis | One of the pathways of mannitol-mediated apoptosis is through the degradation of FAK and Akt and that IGF-I protects the cells from apoptosis by blocking the activation of caspases@ which may be responsible for the loss of FAK and Akt. [ ADR Type 2 ] | Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt |
This panel provides information on drug category
| Toxicity | Source |
|---|