| Protein Name: | Protein tyrosine phosphatase (Q05209) |
|---|---|
| Gene Name: | PTPN12 |
| Description: | Tyrosine-protein phosphatase non-receptor type 12 (EC 3 1 3 48) (Protein-tyrosine phosphatase G1) (PTPG1) |
| PDB ID: | 5J8R |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Adenosine | Apoptosis | PTPase(s) plays an integral role in the induction of EC apoptosis upon exposure to homocysteine and/or adenosine@ possibly by the attenuation of p38alpha activity [ ADR Type 2 ] | Adenosine induces endothelial apoptosis by activating protein tyrosine phosphatase: a possible role of p38alpha |
| homocysteine | Apoptosis | PTPase(s) plays an integral role in the induction of EC apoptosis upon exposure to homocysteine and/or adenosine@ possibly by the attenuation of p38alpha activity [ ADR Type 2 ] | Adenosine induces endothelial apoptosis by activating protein tyrosine phosphatase: a possible role of p38alpha |
This panel provides information on drug category
| Toxicity | Source |
|---|