Protein Name: | Abscisic acid-inducible protein kinase (Q02066) |
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Gene Name: | Not Available |
Description: | Abscisic acid-inducible protein kinase (EC 2 7 11 1) (Fragment) |
PDB ID: | |
Protein Family: | |
Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
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Etoposide | Apoptosis | Induction of apoptotic cell death and DNA damage by treatment of U937 cells with etoposide (100 microM) was associated with a modest@ but sustained@ recruitment of the mitogen-activated protein kinases p42-extracellular signal receptor-activated kinase (ERK)1 and p44-extracellular signal receptor-activated kinase 2. [ ADR Type 2 ] | Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation |
Fentanyl | Pain | PKCgamma as a key element that links opioid receptor activation with the recruitment of opposite systems to opioid analgesia involved in a physiological compensatory pain enhancement [ ADR Type 2 ] | Prevention of fentanyl-induced delayed pronociceptive effects in mice lacking the protein kinase Cgamma gene |
This panel provides information on drug category
Toxicity | Source |
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