| Protein Name: | mitochondrial transcription factor A (Q00059) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
| PDB ID: | 3FGH |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zidovudine | Mitochondrial Defects | AZT treatment could alter the expression of the mitochondrial transcription factor A (mtTFA)@ a key molecule involved in mitochondrial DNA (mtDNA) replication and transcription@indicating that AZT induces mitochondrial defects primarily in muscles with the highest oxidative capacities (heart and RG) [ ADR Type 2 ] | Zidovudine (AZT) induced alterations in mitochondrial biogenesis in rat striated muscles |
This panel provides information on drug category
| Toxicity | Source |
|---|