InAADR: Drug-Protein-ADRs database

Protein Information

Protein Name:	Potassium voltage-gated channel subfamily KQT member 2 (O43526)
Gene Name:	KCNQ2
Description:
PDB ID:	5J03
Protein Family:	PF00520
Protein Category:	Ion Channels

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs	Toxicity	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source
Convulsions	A reduced K+ current due to a novel mutation in KCNQ2 causes neonatal convulsions
Epilepsy	KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier
Seizures	Deletions or duplications in KCNQ2 can cause benign familial neonatal seizures