| Protein Name: | Peptidyl-glycine alpha-amidating monooxygenase (P19021) |
|---|---|
| Gene Name: | PAM |
| Description: | Peptidyl-glycine alpha-amidating monooxygenase precursor (EC 114173) (PAM) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Reserpine | Large Dense Core Vesicles | Those of carboxypeptidase H and the alpha-amidating monooxygenase could only be determined in the paraventricular nucleus@which stimulated neurons and leads to an increased synthesis of secretory peptides and consequently to large dense core vesicles filled with higher quanta of peptides. [ ADR Type 1 ] | Reserpine causes differential changes in the mRNA levels of chromogranin B, secretogranin II, carboxypeptidase H, alpha-amidating monooxygenase, the vesicular amine transporter and of synaptin/synaptophys |
This panel provides information on drug category
| Toxicity | Source |
|---|