| Protein Name: | Carnitine O-acetyltransferase (P43155) |
|---|---|
| Gene Name: | CRAT |
| Description: | Carnitine O-acetyltransferase (EC 2317) (Carnitine acetylase) (CAT) (Carnitine acetyltransferase) (CrAT) |
| PDB ID: | 1NM8 |
| Protein Family: | |
| Protein Category: | Transporters |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Clofibrate | Hyperplasia | Clofibrate induced the activities of carnitine acetyltransferase (90-fold) and NADP-linked malic enzyme (3-fold) to the same level in periportal as in perivenous hepatocytes@associate with marked liver enlargement and hyperplasia. [ ADR Type 2 ] | Clofibrate induces carnitine acyltransferases in periportal and perivenous zones of rat liver and does not disturb the acinar zonation of gluconeogenesis |
This panel provides information on drug category
| Toxicity | Source |
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