| Protein Name: | Dipeptidylpeptidase IV (P42658) |
|---|---|
| Gene Name: | DPP6 |
| Description: | Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX) |
| PDB ID: | 1XFD |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Gentamicin | Consequences Upon Renal Function And Metabolism | Dipeptidylpeptidase IV activity was significantly decreased only after 6 days of treatment with gentamicin@which suggests that gentamicin-induced decrease in ectopeptidase activities could compromise vasoactive and other biologically active peptides handling@ with important consequences upon renal function and metabolism [ ADR Type 1 ] | IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis |
| Mercuric Chloride | Consequences Upon Renal Function And Metabolism | Dipeptidylpeptidase IV activities were markedly decreased (p [ ADR Type 1 ] | IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis |
This panel provides information on drug category
| Toxicity | Source |
|---|