InAADR

Protein Information

Protein Name: Aquaporin-2 (P41181)
Gene Name: AQP2
Description: Aquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein for renal collecting duct) (ADH water channel) (Collecting duct water channel protein) (WCH-CD)
PDB ID: 4NEF
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
diuretics Hypertension The expression and shuttling of AQP2 proteins were increased in the cortex and outer medulla following the treatment with DOCA@which may be causally related with the development of hypertension. [ ADR Type 1 ] Increased expression and shuttling of aquaporin-2 water channels in the kidney in DOCA-salt hypertensive rats

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database