| Protein Name: | corticotropin-releasing hormone (CRH) (P34998) |
|---|---|
| Gene Name: | CRHR1 |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Topiramate | Mood-Stabilizing Effects | Topiramate normalizes hippocampal NPY-LI in flinders sensitive line #depressed# rats and upregulates NPY@ galanin@ and CRH-LI in the hypothalamus@which plays a role for mood-stabilizing and weight loss-inducing effects. [ ADR Type 2 3 ] | A Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-induce |
| Topiramate | Weight Loss-Inducing Effects | Topiramate normalizes hippocampal NPY-LI in flinders sensitive line #depressed# rats and upregulates NPY@ galanin@ and CRH-LI in the hypothalamus@which plays a role for mood-stabilizing and weight loss-inducing effects. [ ADR Type 2 3 ] | A Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-induce |
This panel provides information on drug category
| Toxicity | Source |
|---|