| Protein Name: | D-dopachrome decarboxylase (P30046) |
|---|---|
| Gene Name: | DDT |
| Description: | D-dopachrome decarboxylase (EC 4 1 1 84) (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II) |
| PDB ID: | 1DPT |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Amphotericin B | Significant Cell Death Inhibition Of Enzymatic Activities Of B16/F10 Melanoma Cells | The higher concentrations of antifungal reagent Fungizone (amphotericin B and deoxycholate) caused a significant cell death and the inhibition of enzymatic activities of B16/F10 melanoma cells through activation in dopachrome tautomerase and dopa oxidase activities [ ADR Type 1 ] | Cyclosporine A and prednisone-associated osteoporosis in heart transplant recipients |
| deoxycholate | Significant Cell Death Inhibition Of Enzymatic Activities Of B16/F10 Melanoma Cells | The higher concentrations of antifungal reagent Fungizone (amphotericin B and deoxycholate) caused a significant cell death and the inhibition of enzymatic activities of B16/F10 melanoma cells through activation in dopachrome tautomerase and dopa oxidase activities. [ ADR Type 1 ] | Cyclosporine A and prednisone-associated osteoporosis in heart transplant recipients |
This panel provides information on drug category
| Toxicity | Source |
|---|