InAADR

Protein Information

Protein Name: Choline O-acetyltransferase (P28329)
Gene Name: CHAT
Description: Choline O-acetyltransferase (EC 2316) (CHOACTase) (Choline acetylase) (ChAT)
PDB ID: 2FY2
Protein Family:
Protein Category: Enzyme

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Nicotine Development Of Tolerance A small change in hippocampal choline acetyltransferase activity may have occurred@suggesting that tolerance to nicotine is regulated by genetic factors and that changes in brain nicotinic receptor numbers are to explain the development of tolerance. [ ADR Type 3 ] Nicotine-induced tolerance and receptor changes in four mouse strains

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database