InAADR

Protein Information

Protein Name: Brain-derived neurotrophic factor (P23560)
Gene Name: BDNF
Description: Brain-derived neurotrophic factor precursor (BDNF) (Abrineurin)
PDB ID: 1B8M
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Haloperidol Detrimental Side Effects Three days of haloperidol administration dramatically decreased BDNF immunostaining in the neurons @showing that blockade of dopaminergic receptors with haloperidol rapidly downregulates BDNF in reward and emotional centers of the brain@which leads to the efficacious or detrimental side effects of classical neuroleptic drugs [ ADR Type 5 ] Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database