| Protein Name: | Thromboxane A2 receptor (P21731) |
|---|---|
| Gene Name: | TBXA2R |
| Description: | Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: | Membrane Receptors |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Acetylsalicylic acid | Thrombotic Complications | Aspirin completely abolished thromboxane A2 generation by both control and uraemic platelets@exposing patients to the thrombotic complications of arteriovenous shunts [ ADR Type 2 ] | Moderate doses of aspirin and risk of bleeding in renal failure |
This panel provides information on drug category
| Toxicity | Source |
|---|---|
| Lung Oedema | Thromboxane A2 inhibitors and iloprost prevent angiotensin II-induced oedema in the isolated perfused rat lung |