InAADR

Protein Information

Protein Name: cAMP-dependent protein kinase (P17612)
Gene Name: PRKACA
Description: cAMP-dependent protein kinase, alpha-catalytic subunit (EC 271111) (PKA C-alpha)
PDB ID: 2GU8
Protein Family:
Protein Category: Enzyme

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Glucagon Cell Death Direct pharmacological evidence for the activation of the cAMP-dependent protein kinase in response to glucagon in the intact cell@which leads to cell death. [ ADR Type 2 ] A study of the mechanism of glucagon-induced protein phosphorylation in isolated rat hepatocytes using (Sp)-cAMPS and (Rp)-cAMPS, the stimulatory and inhibitory diastereomers of adenosine cyclic 3',5'-phosphor

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database