| Protein Name: | Junction plakoglobin (P14923) |
|---|---|
| Gene Name: | JUP |
| Description: | Junction plakoglobin (Desmoplakin-3) (Desmoplakin III) |
| PDB ID: | 3IFQ |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Estradiol | Cells To Form Multilayers | Treatment with estradiol caused the rearrangement of subapical/basolateral F-actin and plakoglobin staining into a more uniform pattern@SO the gradual loss of vinculin from cell-matrix and cell-cell adherens junctions of the monolayer could be a potential factor in the capacity of these cells to form multilayers or nodules in postconfluent growth [ ADR Type 2 ] | 17-beta-Estradiol induced alterations of cell-matrix and intercellular adhesions in a human mammary carcinoma cell line |
This panel provides information on drug category
| Toxicity | Source |
|---|