| Protein Name: | Myb proto-oncogene protein (P10242) |
|---|---|
| Gene Name: | MYB |
| Description: | Myb proto-oncogene protein (C-myb) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Apoptosis | Differential apoptosis by indomethacin in gastric epithelial cells through the constitutive expression of wild-type p53 and/or up-regulation of c-myc [ ADR Type 2 ] | Differential apoptosis by indomethacin in gastric epithelial cells through the constitutive expression of wild-type p53 and/or up-regulation of c-myc |
| Mitoxantrone | Cell Death | Intracellularly@ mitoxantrone-induced programmed cell death (PCD) was associated with a marked induction of c-jun and significant repression of c-myc and BCL-2 oncogenes [ ADR Type 3 ] | High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells |
This panel provides information on drug category
| Toxicity | Source |
|---|