| Protein Name: | Heme oxygenase 1 (P09601) |
|---|---|
| Gene Name: | HMOX1 |
| Description: | Heme oxygenase 1 (EC 1 14 99 3) (HO-1) |
| PDB ID: | 1N3U |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Dexamethasone | Oxidative Injury | Dexamethasone inhibits IL-6 and heme-induced HO-1 expression in rabbit coronary endothelial cells@leading to promote oxidative injury such as endotoxins and heme@ which is carried out by activation of a transcriptional protein in competition with the STAT3 binding site [ ADR Type 5 ] | Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone |
This panel provides information on drug category
| Toxicity | Source |
|---|