| Protein Name: | Neprilysin (P08473) |
|---|---|
| Gene Name: | MME |
| Description: | Neprilysin (EC 342411) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 2411) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen) |
| PDB ID: | 1DL9 |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Cyclosporine | Hypertension | CysA increased plasma plasma neutral endopeptidase activity@indicating that chronic NEP inhibition may prevent the CysA-induced hypertension. [ ADR Type 1 ] | Effects of chronic neutral endopeptidase inhibition in rats with cyclosporine-induced hypertension |
This panel provides information on drug category
| Toxicity | Source |
|---|