InAADR

Protein Information

Protein Name: Beta-2 adrenergic receptor (P07550)
Gene Name: ADRB2
Description:
PDB ID: 1GQ4
Protein Family: PF00001, PS00237
Protein Category: Membrane Receptors

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Bambuterol hydrochloride Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to agonist-induced desensitization@cardiovascular effects. [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Exemestane Oedema Not Available Large-scale prediction and testing of drug activity on side-effect targets
Formoterol Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to agonist-induced desensitization@cardiovascular effects. [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Loxapine Tachycardia Not Available Large-scale prediction and testing of drug activity on side-effect targets
Methylphenidate Hepatotoxicity Methylphenidate responds to beta(2)-adrenoreceptor stimulation@which leads to methylphenidate hepatotoxicity. [ ADR Type 2 ] Adrenergic modulation of hepatotoxicity
Prednisone Depression Not Available Large-scale prediction and testing of drug activity on side-effect targets
Reproterol hydrochloride Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to aGOnist-induced desensitization@cardiovascular effects [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Salbutamol Myelosuppression Myelosuppression [ ADR Type 1 ] The pharmacogenetics of beta2-adrenergic receptors: relevance to asthma
Salmeterol Cardiovascular Effects Bronchodilatation@ susceptibility to aGOnist-induced desensitization@cardiovascular effects [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Salmeterol Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to aGOnist-induced desensitization@cardiovascular effects [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Terbutaline Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to aGOnist-induced desensitization@cardiovascular effects [ ADR Type 1 ] Beta2-adrenergic receptor genetics
Tulobuterol hydrochloride Desensitization Cardiovascular Effects Bronchodilatation@ susceptibility to agonist-induced desensitization@cardiovascular effects. [ ADR Type 1 ] Beta2-adrenergic receptor genetics

This panel provides information on drug category

Toxicity Source
Angina Pectoris Large-scale prediction and testing of drug activity on side-effect targets
Anxiety Large-scale prediction and testing of drug activity on side-effect targets
Arrhythmia Large-scale prediction and testing of drug activity on side-effect targets
Atrioventricular Block Large-scale prediction and testing of drug activity on side-effect targets
Bradycardia Large-scale prediction and testing of drug activity on side-effect targets
Bronchospasm Large-scale prediction and testing of drug activity on side-effect targets
Cardiac Arrest Large-scale prediction and testing of drug activity on side-effect targets
Cardiac Failure Large-scale prediction and testing of drug activity on side-effect targets
Cardiac Failure Congestive Large-scale prediction and testing of drug activity on side-effect targets
Dry Eye Large-scale prediction and testing of drug activity on side-effect targets
Fear Large-scale prediction and testing of drug activity on side-effect targets
Myocardial Infarction Large-scale prediction and testing of drug activity on side-effect targets
Neurotoxicity Large-scale prediction and testing of drug activity on side-effect targets
Palpitations Large-scale prediction and testing of drug activity on side-effect targets
Peripheral Coldness Large-scale prediction and testing of drug activity on side-effect targets
Raynaud Phenomenon Large-scale prediction and testing of drug activity on side-effect targets
Sleep Disorder Large-scale prediction and testing of drug activity on side-effect targets
Tachycardia Large-scale prediction and testing of drug activity on side-effect targets
Tension Large-scale prediction and testing of drug activity on side-effect targets
Tremor Large-scale prediction and testing of drug activity on side-effect targets
Vasodilatation Large-scale prediction and testing of drug activity on side-effect targets
Ventricular Arrhythmia Large-scale prediction and testing of drug activity on side-effect targets

InAADR: Drug-Protein-ADRs database