| Protein Name: | retinoblastoma protein (PRb) (P06400) |
|---|---|
| Gene Name: | RB1 |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Inhibition Of Endothelial Cell Proliferation | Indomethacin inhibits endothelial cell proliferation by suppressing cell cycle proteins and PRB phosphorylation@suggestting that indomethacin arrests endothelial cell proliferation essential for angiogenesis by modulating cell cycle protein levels. [ ADR Type 2 ] | Release of calcitonin gene-related peptide (CGRP) from guinea pig dura mater in vitro is inhibited by sumatriptan but unaffected by nitric oxide |
This panel provides information on drug category
| Toxicity | Source |
|---|