| Protein Name: | Insulin-like growth factor I (P05017) |
|---|---|
| Gene Name: | Not Available |
| Description: | Insulin-like growth factor I precursor (IGF-I) (Somatomedin) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Dehydrated Alcohol | Impairs Insulin | EtOH altered the distribution of eukaryotic initiation factor (eIF)4E@ as evidenced by a decreased amount of active eIF4E eIF4G complex@ an increased amount of inactive eIF4E-binding protein (BP)1 complex@ and decreased 4E-BP1 phosphorylation@which impairs insulin and IGF-I stimulation of S6K1 [ ADR Type 2 ] | Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle |
This panel provides information on drug category
| Toxicity | Source |
|---|