| Protein Name: | Metallothionein (P04731) |
|---|---|
| Gene Name: | MT1A |
| Description: | Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Auranofin | Persistent Loose Stools | Developed persistent loose stools. [ ADR Type 2 ] | Auranofin treatment of rats: adaptation to intestinal adverse effects and observations on the cytosolic distribution of gold in the intestines, liver and kidneys |
| Caffeine | Hepatotoxicity | Caffeine reduced significantly the magnitude of ACM-induced mobilization of cadmium from hepatic cadmium-Metallothionein stores,which leads to acetaminophen-induced hepatotoxicity. [ ADR Type 1 ] | Acetaminophen-induced hepatotoxicity: antagonistic action of caffeine in mice |
| Copper | Abnormal Metallothionein Gene Regulation | Abnormal metallothionein gene regulation in response to copper [ ADR Type 2 ] | Menkes' disease: abnormal metallothionein gene regulation in response to copper |
This panel provides information on drug category
| Toxicity | Source |
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