| Protein Name: | NADH-ubiquinone oxidoreductase chain 1 (P03886) |
|---|---|
| Gene Name: | CES1 |
| Description: | NADH-ubiquinone oxidoreductase chain 1 (EC 1 6 5 3) (NADH dehydrogenase subunit 1) |
| PDB ID: | |
| Protein Family: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Chlorpromazine | Parkinsonism | Chlorpromazine produces parkinsonism apparently through inhibition of NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial electron transport chain. [ ADR Type 1 ] | Neuroleptic medications inhibit complex I of the electron transport chain |
| Haloperidol | Parkinsonism | Haloperidol produces parkinsonism apparently through inhibition of NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial electron transport chain. [ ADR Type 1 ] | Neuroleptic medications inhibit complex I of the electron transport chain |
| Thiothixene | Parkinsonism | Thiothixene produces parkinsonism apparently through inhibition of NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial electron transport chain [ ADR Type 1 ] | Neuroleptic medications inhibit complex I of the electron transport chain |
This panel provides information on drug category
| Toxicity | Source |
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