| Protein Name: | wild-type p53 (P00062) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Acetylsalicylic acid | Apoptosis In Human Colon Cancer Cells | Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells [ ADR Type 1 ] | Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells |
| Phylloquinone | Apoptosis | Menadione at 1-20 microM induced wild-type P53,and thus Apoptosis induced by lower concentrations of menadione may be mediated by wild-type P53. [ ADR Type 1 ] | Menadione induces both necrosis and apoptosis in rat pancreatic acinar AR4-2J cells |
This panel provides information on drug category
| Toxicity | Source |
|---|