| Protein Name: | protein kinases ERK (P00048) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Cisplatin | Cell Death | Activation of the mitogen-activated protein kinases ERK1/2 by the chemotherapeutic agent cisplatin has been shown to result in either survival or cell death [ ADR Type 2 ] | Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines Cancer |
This panel provides information on drug category
| Toxicity | Source |
|---|