| Protein Name: | IkappaB kinase complex-associated protein (O95163) |
|---|---|
| Gene Name: | IKBKAP |
| Description: | IkappaB kinase complex-associated protein (IKK complex-associated protein) (p150) |
| PDB ID: | 5CQR |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Melphalan | Expose P815 Tumor Cells To Oxidative Stress | Exposure of P815 tumor cells to a cell-permeable peptide that selectively inhibits NF-kappaB activation by blocking the activation of the IkappaB-kinase complex was found to inhibit the L-PAM-induced B7-1 mRNA accumulation,which exposes P815 tumor cells to oxidative stress [ ADR Type 2 ] | Mechanism of melphalan-induced B7-1 gene expression in P815 tumor cells |
This panel provides information on drug category
| Toxicity | Source |
|---|