| Protein Name: | Adenosylhomocysteinase (O43865) |
|---|---|
| Gene Name: | AHCYL1 |
| Description: | Putative adenosylhomocysteinase 2 (EC 3 3 1 1) (S-adenosyl-L- homocysteine hydrolase 2) (AdoHcyase 2) (S-adenosylhomocysteine hydrolase-like 1) (DC-expressed AHCY-like molecule) |
| PDB ID: | 3MTG |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| MDL-28842 | Apoptosis | Apoptosis induced by the inhibition of S-adenosylhomocysteine hydrolase with MDL-28842. [ ADR Type 2 ] | Adenosine induces endothelial apoptosis by activating protein tyrosine phosphatase: a possible role of p38alpha |
| Nifedipine | Side Effects | Inhibition of an enzyme involved in transmethylation reactions was observed in patients during arabinoside(ara-A) therapy,which could contribute to the side effects and antiviral properties of ara-A [ ADR Type 1 ] | Inactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapy |
This panel provides information on drug category
| Toxicity | Source |
|---|