| Protein Name: | 7-ethoxycoumarin O-deethylase (O23976) |
|---|---|
| Gene Name: | CYP76B1 |
| Description: | Cytochrome P450 76B1 (EC 114--) (7-ethoxycoumarin O-deethylase) (ECOD) (Phenylurea dealkylase) |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Acetaminophen | Renal Functional Changes | Kidneys from F344 rats displayed greater concentrations of P-450 and greater ethoxycoumarin-o-deethylase activity than kidneys from SD rats,reflecting APAP-induced renal functional changes. [ ADR Type 1 ] | Acetaminophen nephrotoxicity in the rat I Strain differences in nephrotoxicity and metabolism |
This panel provides information on drug category
| Toxicity | Source |
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