InAADR

Protein Information

Protein Name: Tumor protein p73 (O15350)
Gene Name: TP73
Description: Tumor protein p73 (p53-like transcription factor) (p53-related protein)
PDB ID: 1COK
Protein Family:
Protein Category:

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Cisplatin Cytotoxicity c-Abl and p73 are components of a mismatch-repair-dependent apoptosis pathway which contributes to cisplatin-induced cytotoxicity [ ADR Type 2 ] The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database