Protein Name: | Tumor protein p73 (O15350) |
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Gene Name: | TP73 |
Description: | Tumor protein p73 (p53-like transcription factor) (p53-related protein) |
PDB ID: | 1COK |
Protein Family: | |
Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
Interacting Drugs | Toxicity | Mechanism | Reference |
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Cisplatin | Cytotoxicity | c-Abl and p73 are components of a mismatch-repair-dependent apoptosis pathway which contributes to cisplatin-induced cytotoxicity [ ADR Type 2 ] | The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage |
This panel provides information on drug category
Toxicity | Source |
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