InAADR

Protein Information

Protein Name: NMDA receptor-regulated protein 1 (Q8TCU5)
Gene Name: CYP2D6
Description: Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L)
PDB ID:
Protein Family:
Protein Category: Ion Channels

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
interferon gamma Excitotoxic Mechanisms Of Injury NO acts directly upon immature neurones but indirectly@ via NMDA receptors@ on more mature neurones@showing a complex interaction between inflammatory and excitotoxic mechanisms of injury in mature neurones [ ADR Type 2 ] A Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database