| Protein Name: | Matrix metalloproteinase (P50281) |
|---|---|
| Gene Name: | MMP14 |
| Description: | Matrix metalloproteinase-14 precursor (EC 3 4 24 80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1) |
| PDB ID: | 1BQQ |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Pentoxifylline | Antifibrogenic Action | Incubation with PTF increased the levels of #activated MMP-1# in cell supernatants in both basal and stimulated conditions,suggest that the antifibrogenic action of PTF on human HSCs is mainly mediated by extracellular collagen degradation [ ADR Type 1 ] | Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-beta |
This panel provides information on drug category
| Toxicity | Source |
|---|