| Protein Name: | Macrophage migration inhibitory factor (P14174) |
|---|---|
| Gene Name: | MIF |
| Description: | Macrophage migration inhibitory factor (MIF) (Phenylpyruvate tautomerase) (EC 5321) (Glycosylation-inhibiting factor) (GIF) |
| PDB ID: | 1CA7 |
| Protein Family: | |
| Protein Category: | Enzyme | Membrane Protein |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Neuroleptics | Hypomotility | Melanotropin release inhibiting factor (MIF) and its analog cyclo(Leu-Gly) (CLG) facilitate dopamine (DA) receptor agonist binding and inhibit DA receptor supersensitivity induced by neuroleptics and opiates@which leads to hypomotility. [ ADR Type 1 ] | Effect of cyclo(Leu-Gly) on reserpine-induced hypomotility and increases in cortical beta-adrenergic receptors |
This panel provides information on drug category
| Toxicity | Source |
|---|