InAADR: Drug-Protein-ADRs database

InAADR

Enter Protein Name or Uniprot ID:

Protein Information

Protein Name:	Insulin receptor precursor (P06213)
Gene Name:	INSR
Description:
PDB ID:	1GAG
Protein Family:	PF00757, PS50853
Protein Category:	Enzyme

Drug-Protein Interaction
Adverse Drug Reactions

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs	Toxicity	Mechanism	Reference
Sertraline	Convulsion	Not Available	Large-scale prediction and testing of drug activity on side-effect targets

This panel provides information on drug category

Toxicity	Source
Acanthosis Nigricans	Association of insulin resistance with hyperandrogenia in women
Diabetes Mellitus	Long-term follow up in type A insulin resistant syndrome treated by insulin-like growth factor I
Hyperglycemia	Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice
Polycystic Ovary Syndrome	Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome
Type 2 Diabetes	Enzyme occupancy measurement of intracellular protein tyrosine phosphatase 1B using photoaffinity probes

InAADR: Drug-Protein-ADRs database