| Protein Name: | Fatty acid synthase (P49327) |
|---|---|
| Gene Name: | FASN |
| Description: | Fatty acid synthase (EC 2 3 1 85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2 3 1 38); [Acyl-carrier-protein] S- malonyltransferase (EC 2 3 1 39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2 3 1 41); 3-oxoacyl-[acyl-carrier-protein] r |
| PDB ID: | 1XKT |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Lindane | Affect Fatty Acid Synthesis | Lindane in the refeeding diet blunted this overshoot of FAS and CCE activities in a dose-dependent manner@suggesting that lindane and PCBs affect fatty acid synthesis at opposite points [ ADR Type 1 ] | A The effect of gamma-hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats Z Naturforsch [C] |
This panel provides information on drug category
| Toxicity | Source |
|---|