| Protein Name: | cytochrome P450 (E2RWL6) |
|---|---|
| Gene Name: | CYP1A1 |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Cisplatin | Nephrotoxicity | Treatment of rats with cisplatin or with cisplatin after chronic pre-exposure to cadmium induced a decrease in kidney cytochrome P-450 and glutathione levels, and in glutathione peroxidase and reductase activities And cadmium nephrotoxicity was characterized by tubular proximal damage with mitochondrial and lysosomal changes and a widespread vesiculation of tubular cells [ ADR Type 1 ] | Cisplatin nephrotoxicity in cadmium-pretreated rats Enzymatic, functional and morphological studies |
This panel provides information on drug category
| Toxicity | Source |
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