| Protein Name: | Chromaffin granule amine transporter (P54219) |
|---|---|
| Gene Name: | SLC18A1 |
| Description: | Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: | Transporters |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Reserpine | Large Dense Core Vesicles | Vesicular amine transporter was found in substantia nigra compacta@ the dorsal raphe and the locus coeruleus@which stimulated neurons and leads to an increased synthesis of secretory peptides and consequently to large dense core vesicles filled with higher quanta of peptides [ ADR Type 1 ] | Reserpine causes differential changes in the mRNA levels of chromogranin B, secretogranin II, carboxypeptidase H, alpha-amidating monooxygenase, the vesicular amine transporter and of synaptin/synaptophys |
This panel provides information on drug category
| Toxicity | Source |
|---|