| Protein Name: | Arylamine N-acetyltransferase 2 (P11245) |
|---|---|
| Gene Name: | NAT2 |
| Description: | Arylamine N-acetyltransferase 2 (EC 2 3 1 5) (Arylamide acetylase 2) (Arylamine N-acetyltransferase, polymorphic) (PNAT) (N- acetyltransferase type 2) (NAT-2) |
| PDB ID: | 2PFR |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Co-trimoxazole | Granulocytopenia | Granulocytopenia with anemization [ ADR Type 2 ] | Acute-phase response in rat to carbon tetrachloride-azathioprine induced cirrhosis and partial hepatectomy of cirrhotic liver |
| Co-trimoxazole | Liver Impairment | Liver impairment [ ADR Type 2 ] | Acute-phase response in rat to carbon tetrachloride-azathioprine induced cirrhosis and partial hepatectomy of cirrhotic liver |
| Co-trimoxazole | Rash | Rash [ ADR Type 5 ] | Acute-phase response in rat to carbon tetrachloride-azathioprine induced cirrhosis and partial hepatectomy of cirrhotic liver |
| Ibuprofen | Ibuprofen Inhibition | Ibuprofen inhibition of Arylamine n-acetyltransferase activity and ibuprofen inhibition of growth in the bacterium H. pylori. [ ADR Type 1 ] | Ibuprofen affects arylamine N-acetyltransferase activity in Helicobacter pylori from peptic ulcer patients |
This panel provides information on drug category
| Toxicity | Source |
|---|