InAADR

Drug Information

Drug Name: mianserin (24219-97-4)
PubChem ID: 4184
SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42
InchiKey: UEQUQVLFIPOEMF-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic alpha-Antagonists, Adrenergic Antagonists, Antidepressive Agents, Central Nervous System Agents, Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Neurotransmitter Agents, Psychotropic Drugs, Serotonin Agents, Serotonin Antagonists

Computed Drug Properties

Molecular Weight (dalton): 264.372
LogP: 3.0839
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 6.48

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Toxicity And Inefficacy CYP2D6 (P10635) Toxicity in poor metabolisers@ inefficacy in ultrarapid metabolisers. [ ADR Type 3 ] Drugs in special patient groups: clinical importance of genomics in drug effects In: Carruthers GS, Hoffmann BB,Melmon KL, Nierenberg DW

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abnormal Behaviour MetaADEDB
Abscess Jaw MetaADEDB
Accident At Home MetaADEDB
Acidosis MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Adenocarcinoma MetaADEDB
Adenoviral Haemorrhagic Cystitis MetaADEDB
Adh Inappropriate MetaADEDB
Affective Disorder MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Aids Encephalopathy MetaADEDB
Akathisia Drug-Induced MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Alveolitis MetaADEDB
Alpha 1 Globulin Increased MetaADEDB
Als MetaADEDB
Altered State Of Consciousness MetaADEDB
Amniocentesis Abnormal MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anger MetaADEDB
Anorexia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anuria MetaADEDB
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Application Site Dermatitis MetaADEDB
Arrhythmia Supraventricular MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Attempted Suicide MetaADEDB
Automatism MetaADEDB
Bacillus Infection MetaADEDB
Bacterial Sepsis MetaADEDB
Bacterial Test Positive MetaADEDB
Bacterial Toxaemia MetaADEDB
Behcet Syndrome MetaADEDB
Bile Duct Obstruction MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Bipolar Disorder MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blepharoptosis MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Immunoglobulin A Decreased MetaADEDB
Blood Immunoglobulin G Decreased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Development Abnormal MetaADEDB
Bone Trimming MetaADEDB
Bradycardia MetaADEDB
Bradypnoea MetaADEDB
Breast Cancer Recurrent MetaADEDB
Brugada Syndrome MetaADEDB
Bulbar Palsy MetaADEDB
Bulging MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Serology Positive MetaADEDB
Carcinoid Syndrome MetaADEDB
Catalepsy MetaADEDB
Cataract MetaADEDB
Cell Death MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervical Dysplasia MetaADEDB
Cervix Disorder MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Circadian Rhythm Sleep Disorder MetaADEDB
Coagulation Test Abnormal MetaADEDB
Cognitive Disorder MetaADEDB
Coma MetaADEDB
Communication Disorder MetaADEDB
Concomitant Disease Progression MetaADEDB
Confabulation MetaADEDB
Congenital Hand Malformation MetaADEDB
Congenital Musculoskeletal Anomaly MetaADEDB
Congenital Poikiloderma MetaADEDB
Coordination Abnormal MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coughing Blood MetaADEDB
Craniofacial Abnormalities MetaADEDB
Creatinine Urine Decreased MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cytolytic Hepatitis MetaADEDB
Decreased Activity MetaADEDB
Delusion MetaADEDB
Delusional Disorder Persecutory Type MetaADEDB
Dental Prosthesis Placement MetaADEDB
Depersonalisation MetaADEDB
Depressed Mood MetaADEDB
Depressive Disorder MetaADEDB
Derealisation MetaADEDB
Dermatitis Bullous MetaADEDB
Dextrocardia MetaADEDB
Diabetes MetaADEDB
Dialysis MetaADEDB
Diaphragmatic Hernia MetaADEDB
Disease Of Liver MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disturbance In Attention MetaADEDB
Drowsiness MetaADEDB
Drug Effect Increased MetaADEDB
Drug Interaction MetaADEDB
Dysmorphism MetaADEDB
Dystonia MetaADEDB
Dysuria MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Encephalopathy MetaADEDB
Eosinophil Count Increased MetaADEDB
Escherichia Infection MetaADEDB
Escherichia Sepsis MetaADEDB
Excess Potassium MetaADEDB
Excessive Granulation Tissue MetaADEDB
Extrapyramidal Disorder MetaADEDB
Eye Rolling MetaADEDB
Face Pain MetaADEDB
Feeling Drunk MetaADEDB
Femur Fracture MetaADEDB
Food Craving MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Ulcer MetaADEDB
General Physical Condition MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Glomerulonephritis Minimal Lesion MetaADEDB
Haematoma MetaADEDB
Hallucinations MetaADEDB
Helicobacter Infection MetaADEDB
Hematologic Diseases MetaADEDB
Hematoma Subdural MetaADEDB
Hemiparesis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Neoplasia MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatocellular Injury MetaADEDB
Humerus Fracture MetaADEDB
Hyperammonaemia MetaADEDB
Hypercreatininaemia MetaADEDB
Hypergammaglobulinaemia MetaADEDB
Hyperhidrosis MetaADEDB
Hyperkinesis MetaADEDB
Hyperreflexia MetaADEDB
Hypertension MetaADEDB
Hyperventilation MetaADEDB
Hypoaesthesia MetaADEDB
Hypopharyngeal Cancer MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypothermia MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Impulse Control Disorders MetaADEDB
Incorrect Drug Administration Duration MetaADEDB
Infusion Related Reaction MetaADEDB
Intentional Misuse MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intracranial Haematoma MetaADEDB
Ischaemic Hepatitis MetaADEDB
Jaw Disorder MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Laparotomy MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Lichenoid Keratosis MetaADEDB
Lipids Increased MetaADEDB
Long Qt Syndrome MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphoma MetaADEDB
Malnourished MetaADEDB
Mastication Disorder MetaADEDB
Mean Cell Haemoglobin Decreased MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Meningioma MetaADEDB
Meningorrhagia MetaADEDB
Mental Disorders MetaADEDB
Metastases To Meninges MetaADEDB
Miosis MetaADEDB
Moebius Ii Syndrome MetaADEDB
Mood Altered MetaADEDB
Motor Retardation MetaADEDB
Movement Disorders MetaADEDB
Mucosal Dryness MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Nasal Sinus Cancer MetaADEDB
Neonatal Respiratory Arrest MetaADEDB
Nephritis Allergic MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Normal Newborn MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Obesity MetaADEDB
Ocular Motility Disorders MetaADEDB
Oliguria MetaADEDB
Osteoarthritis MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pallor MetaADEDB
Panic Attack MetaADEDB
Paranoid Disorders MetaADEDB
Parkinson Disease Secondary MetaADEDB
Periodontitis MetaADEDB
Personality Disorders MetaADEDB
Phlebitis MetaADEDB
Phlebothrombosis MetaADEDB
Poland Syndrome MetaADEDB
Pollakiuria MetaADEDB
Poriomania MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Psychoses MetaADEDB
Pulmonary Hypoplasia MetaADEDB
Pulmonary Radiation Injury MetaADEDB
Pyelonephritis MetaADEDB
Quadriplegia MetaADEDB
Radiation Pneumonitis MetaADEDB
Rash Generalised MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Infarct MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiration Abnormal MetaADEDB
Respiratory Disorder Neonatal MetaADEDB
Reticulocytosis MetaADEDB
Rhabdomyolysis MetaADEDB
Right Heart Failure MetaADEDB
Risus Sardonicus MetaADEDB
Seizures MetaADEDB
Sensation Of Foreign Body MetaADEDB
Sense Of Oppression MetaADEDB
Sexual Dysfunction Physiological MetaADEDB
Skin Hypertrophy MetaADEDB
Spasm MetaADEDB
Speech Disorder MetaADEDB
Spleen Disorder MetaADEDB
Stereotypic Movement Disorder MetaADEDB
Subcutaneous Emphysema MetaADEDB
Subcutaneous Haematoma MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Syndactyly MetaADEDB
Talipes MetaADEDB
Threatened Labour MetaADEDB
Tibia Fracture MetaADEDB
Tooth Disease MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Encephalopathy MetaADEDB
Toxic Skin Eruption MetaADEDB
Tremor MetaADEDB
Ulnar Nerve Palsy MetaADEDB
Urine Output Increased MetaADEDB
Ventricular Hypoplasia MetaADEDB
Vulvovaginal Discomfort MetaADEDB
Wound Dehiscence MetaADEDB

InAADR: Drug-Protein-ADRs database