InAADR

Drug Information

Drug Name: Ursodeoxycholic acid (128-13-2)
PubChem ID: 31401
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
InchiKey: RUDATBOHQWOJDD-UZVSRGJWSA-N
Therapeutic Category: Cholagogues and Choleretics, Gastrointestinal Agents

Computed Drug Properties

Molecular Weight (dalton): 392.58
LogP: 4.4779
Ring Count: 0
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 77.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Dapsone (80-08-0) Effectiveness Of Dapsone In The Treatment Of Dermatitis Herpetiformis Is Reduced Antagonistic Not understood A single case suggests that the effectiveness of dapsone in the treatment of dermatitis herpetiformis may be reduced by ursodeoxycholic acid

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cavity Drainage MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Distension MetaADEDB
Abdominal Pain ADReCS
Abnormal Lfts MetaADEDB
Acidosis MetaADEDB
Acne ADReCS
Acute Coronary Syndrome ADReCS
Acute Graft Versus Host Disease MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Insufficiency MetaADEDB
Adrenalitis MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergy ADReCS
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amblyopia ADReCS
Amnesia ADReCS
Amyloidosis ADReCS
Anaemia ADReCS
Androgen Deficiency MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorexia ADReCS
Anuria MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Arrhythmia ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspergillosis MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block ADReCS
Atrioventricular Block Complete ADReCS
Azotaemia MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Behcet Syndrome MetaADEDB
Bile Duct Diseases MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Cirrhosis Primary MetaADEDB
Biliary Colic ADReCS
Biliary Dilatation MetaADEDB
Biliary Fibrosis MetaADEDB
Biliary Tract Infection MetaADEDB
Black Stools MetaADEDB
Bladder Catheter Temporary MetaADEDB
Bladder Pain ADReCS
Blindness ADReCS
Block Heart SIDER
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Glucose Increased ADReCS
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Immeasurable MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased ADReCS
Bone Disorder ADReCS
Bone Marrow Depression MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Pain ADReCS
Brain Death MetaADEDB
Breast Disorder SIDER
Breast Mass ADReCS
Breast Neoplasm ADReCS
Bronchitis ADReCS
Burning Sensation Mucosal MetaADEDB
Bursitis Infective MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Calcinosis MetaADEDB
Cancer Pain MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Acute MetaADEDB
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiac Output Decreased MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomegaly ADReCS
Cardiomyopathy ADReCS
Cardiovascular Disorder ADReCS
Cataract ADReCS
Catheter Site Infection MetaADEDB
Catheter Site Pain MetaADEDB
Cell Marker Increased MetaADEDB
Cellulitis ADReCS
Cerebellar Ischaemia MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Chills ADReCS
Cholangiolitis MetaADEDB
Cholangitis MetaADEDB
Cholangitis Sclerosing MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis ADReCS
Choledochoenterostomy MetaADEDB
Cholelithiasis MetaADEDB
Cholestasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Cholestasis Intrahepatic Of Pregnancy MetaADEDB
Cholestasis Progressive Familial Intrahepatic 1 MetaADEDB
Chronic Kidney Disease MetaADEDB
Cirrhosis MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cmv Infection MetaADEDB
Cold Sweat MetaADEDB
Colonic Neoplasms MetaADEDB
Colonic Stenosis MetaADEDB
Colorectal Cancer MetaADEDB
Common Wart SIDER
Complications Of Transplanted Liver MetaADEDB
Confusional State ADReCS
Conjunctivitis ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Contralateral Breast Cancer MetaADEDB
Convulsion ADReCS
Cough ADReCS
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatinine Increased SIDER
Crossmatch Incompatible MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cyst ADReCS
Cystic Fibrosis MetaADEDB
Cystitis ADReCS
Cystitis Noninfective ADReCS
Cytomegalovirus Colitis MetaADEDB
Deafness ADReCS
Decreased Appetite ADReCS
Dehydration ADReCS
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Device Related Infection MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus ADReCS
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Neuropathy MetaADEDB
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Distal Intestinal Obstruction Syndrome MetaADEDB
Distress Gastrointestinal SIDER
Dizziness ADReCS
Drug Diversion MetaADEDB
Drug Hypersensitivity ADReCS
Drug Interaction SIDER
Drug Withdrawal MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Ear Disorder ADReCS
Ear Infection ADReCS
Ecchymosis ADReCS
Effusion ADReCS
Electrocardiogram Qt Prolonged MetaADEDB
Encephalitis Allergic MetaADEDB
Endotracheal Intubation MetaADEDB
Enlarged Spleen MetaADEDB
Enterococcal Infection MetaADEDB
Eosinophil Count Decreased MetaADEDB
Eosinophil Count Increased MetaADEDB
Epistaxis ADReCS
Eructation ADReCS
Erythema Multiforme MetaADEDB
Essential Thrombocythaemia MetaADEDB
Eye Disorder SIDER
Face Oedema ADReCS
Fat Atrophy MetaADEDB
Fatigue ADReCS
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Fibrocystic Breast Disease ADReCS
Fibrosis ADReCS
Flatulence ADReCS
Flu Symptoms SIDER
Fluid Retention ADReCS
Gall Bladder MetaADEDB
Gallbladder Diseases MetaADEDB
Gallbladder Operation MetaADEDB
Gallstones MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Disorder ADReCS
Gastric Ulcer ADReCS
Gastritis ADReCS
Gastroenteritis Staphylococcal MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Generalised Oedema ADReCS
Glaucoma MetaADEDB
Glaucomatocyclitic Crises MetaADEDB
Globulinuria MetaADEDB
Glucose Increased SIDER
Glucose Urine MetaADEDB
Graft Versus Host Disease MetaADEDB
Granuloma ADReCS
Haematemesis MetaADEDB
Haematochezia MetaADEDB
Haematoma Evacuation MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemolysis MetaADEDB
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Headache ADReCS
Heat Rash ADReCS
Helicobacter Infection MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Artery Stenosis MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Cancer Metastatic MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatic Infection Bacterial MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis B MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis C MetaADEDB
Hepatitis Chronic MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatobiliary Disease SIDER
Hepatotoxicity MetaADEDB
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Simplex Serology Positive MetaADEDB
Herpes Virus Infection ADReCS
Hiccough MetaADEDB
Hyperammonaemia MetaADEDB
Hyperamylasaemia MetaADEDB
Hyperchloraemia MetaADEDB
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperthyroidism MetaADEDB
Hypertrophic Cardiomyopathy MetaADEDB
Hypertrophy ADReCS
Hypoaesthesia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Encephalopathy MetaADEDB
Hypomagnesaemia MetaADEDB
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothyroidism MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Immunosuppressant Drug Level MetaADEDB
Incontinence ADReCS
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Inflammation MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Induration MetaADEDB
Injection Site Ulcer MetaADEDB
Insomnia ADReCS
Insufficiency Renal SIDER
Interstitial Lung Disease ADReCS
Interstitial Pneumonia SIDER
Intracranial Tumour Haemorrhage MetaADEDB
Intussusception MetaADEDB
Ischaemic Hepatitis MetaADEDB
Jaundice MetaADEDB
Jaundice Obstructive MetaADEDB
Kidney Failure MetaADEDB
Kidney Small MetaADEDB
Laboratory Test Abnormal ADReCS
Laryngeal Oedema ADReCS
Leg Cramps ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Leukoplakia MetaADEDB
Lip Ulceration MetaADEDB
Liver Abscess MetaADEDB
Liver Cirrhosis MetaADEDB
Liver Cirrhosis Biliary MetaADEDB
Liver Diseases MetaADEDB
Liver Failure Acute MetaADEDB
Liver Transplant MetaADEDB
Liver Transplant Rejection MetaADEDB
Loss Of Consciousness ADReCS
Lung Disorder ADReCS
Lung Edema MetaADEDB
Lung Infiltration ADReCS
Lung Neoplasm ADReCS
Lung Nodule SIDER
Lung Transplant MetaADEDB
Lymphadenopathy ADReCS
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mediastinal Disorder SIDER
Melaena ADReCS
Meningitis Fungal MetaADEDB
Menorrhagia ADReCS
Metabolic Encephalopathy MetaADEDB
Metastases To Abdominal Cavity MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastatic Gastric Cancer MetaADEDB
Methaemoglobinaemia MetaADEDB
Micturition Urgency MetaADEDB
Migraine ADReCS
Miliaria SIDER
Mouth Ulcer MetaADEDB
Movement Disorder MetaADEDB
Mucocele MetaADEDB
Multi-Organ Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Mycobacterium Fortuitum Infection MetaADEDB
Myelitis MetaADEDB
Myocardial Infarction ADReCS
Nasal Discomfort ADReCS
Nasal Dryness MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Necrosis MetaADEDB
Necrotising Enterocolitis Neonatal MetaADEDB
Neoplasm ADReCS
Neoplasm Prostate MetaADEDB
Neoplasms MetaADEDB
Nervous System Disorder SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neuroblastoma Recurrent MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Nocturia ADReCS
Nodule ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Varices Haemorrhage MetaADEDB
Oesophagitis ADReCS
Oliguria MetaADEDB
Oral Mucosal Blistering MetaADEDB
Orthostatic Hypotension ADReCS
Osteoporosis MetaADEDB
Otitis SIDER
Otitis Media ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Pancreatic Carcinoma Recurrent MetaADEDB
Pancreatitis ADReCS
Paraesthesia ADReCS
Pathological Fracture ADReCS
Pco2 Decreased MetaADEDB
Peptic Ulcer ADReCS
Pericardial Effusion ADReCS
Pericarditis ADReCS
Peritoneal Adhesions MetaADEDB
Peritoneal Dialysis MetaADEDB
Peritonitis MetaADEDB
Pharyngitis ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Plantar Warts SIDER
Platelet Count MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Po2 Decreased MetaADEDB
Pollakiuria ADReCS
Polyp ADReCS
Porphyrias Hepatic MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Complication MetaADEDB
Postoperative Complications MetaADEDB
Pruritus ADReCS
Psoriasis ADReCS
Pulmonary Fibrosis ADReCS
Pulmonary Hypertension ADReCS
Pyelonephritis Acute MetaADEDB
Radial Nerve Palsy MetaADEDB
Rash ADReCS
Rectal Perforation MetaADEDB
Renal Failure ADReCS
Renal Impairment ADReCS
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Disorder ADReCS
Retrosternal Pain SIDER
Rhinitis ADReCS
Salivary Gland Enlargement ADReCS
Seizures SIDER
Sensation Of Foreign Body MetaADEDB
Septic Shock MetaADEDB
Serratia Bacteraemia MetaADEDB
Serratia Infection MetaADEDB
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sinusitis ADReCS
Skin Discolouration ADReCS
Skin Disorder ADReCS
Skin Hypertrophy ADReCS
Skin Papilloma ADReCS
Skin Ulcer ADReCS
Somnolence ADReCS
Sore Nose SIDER
Speech Disorder MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal X-Ray MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stent Occlusion MetaADEDB
Subacute Hepatic Failure MetaADEDB
Subdural Hygroma MetaADEDB
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Talipes MetaADEDB
Tenderness ADReCS
Tension ADReCS
Thrombocytopenia ADReCS
Thrombotic Microangiopathy MetaADEDB
Thyroid Neoplasia MetaADEDB
Tinnitus ADReCS
Transfusion Microchimerism MetaADEDB
Transfusion-Related Acute Lung Injury MetaADEDB
Transplant Failure MetaADEDB
Transposition Of The Great Vessels MetaADEDB
Trigger Finger MetaADEDB
Tuberculosis Gastrointestinal MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Ulcer ADReCS
Ulcer Haemorrhage ADReCS
Upper Gastrointestinal Bleeding MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urethral Disorder SIDER
Urinary Incontinence ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vasodilation SIDER
Vasodilation Procedure ADReCS
Vertigo ADReCS
Viral Infection ADReCS
Viral Rash MetaADEDB
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vocal Cord Polyp MetaADEDB
Vomiting ADReCS
Weight Increased ADReCS
Weight Loss MetaADEDB

InAADR: Drug-Protein-ADRs database