InAADR

Drug Information

Drug Name: Torasemide (56211-40-6)
PubChem ID: 41781
SMILES: CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C
InchiKey: NGBFQHCMQULJNZ-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Cardiovascular Agents, Diuretics, Membrane Transport Modulators, Natriuretic Agents, Sodium Potassium Chloride Symporter Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 348.428
LogP: 2.52992
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 100.19

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Neoplasm MetaADEDB
Abscess Bacterial MetaADEDB
Abscess Limb MetaADEDB
Accidental Overdose MetaADEDB
Acidosis MetaADEDB
Actinic Elastosis MetaADEDB
Actinic Keratosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Failure MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Consumption MetaADEDB
Alcoholism MetaADEDB
Amaurosis Fugax MetaADEDB
Anaemia MetaADEDB
Anaemia Hypochromic MetaADEDB
Anaemia Postoperative MetaADEDB
Angina MetaADEDB
Angioedema ADReCS
Antinuclear Antibody MetaADEDB
Aortic Dissection MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asystole MetaADEDB
Atrial Fibrillation ADReCS
Atrial Flutter MetaADEDB
Atrial Tachycardia MetaADEDB
Azotaemia MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Balance Disorder MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Bladder Retention MetaADEDB
Bleb MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Homocysteine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Blood Uric Acid Increased ADReCS
Bradyarrhythmia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Bronchopneumonia MetaADEDB
Bulging MetaADEDB
Bundle Branch Block MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calculus Bladder MetaADEDB
Candida Infection MetaADEDB
Candida Sepsis MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carbohydrate Antigen 125 Increased MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Output Decreased MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cardiovascular Insufficiency MetaADEDB
Catheterisation Cardiac MetaADEDB
Cellulitis MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cervix Disorder MetaADEDB
Cheilitis MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Cirrhosis MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Colitis MetaADEDB
Colitis Pseudomembranous MetaADEDB
Complications Of Transplanted Liver MetaADEDB
Condition Aggravated MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Conjunctival Deposit MetaADEDB
Constipation ADReCS
Cough ADReCS
Cough Increased ADReCS
Cushing Syndrome MetaADEDB
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Dermatitis Medicamentosa MetaADEDB
Diabetes MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Dislocation MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Interaction MetaADEDB
Duodenal Ulcer MetaADEDB
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea Exacerbated MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Abnormal ADReCS
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Emphysema MetaADEDB
Encephalopathy MetaADEDB
Endotracheal Intubation MetaADEDB
Enlarged Spleen MetaADEDB
Enterococcal Infection MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Erysipelas MetaADEDB
Erysipeloid MetaADEDB
Erythropenia MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst ADReCS
Extrasystoles Ventricular MetaADEDB
Faecal Incontinence MetaADEDB
Faeces Pale MetaADEDB
Family Stress MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Fistula MetaADEDB
Fistula Repair MetaADEDB
Fluid Intake Reduced MetaADEDB
Fluid Overload MetaADEDB
Focal Glomerulosclerosis MetaADEDB
Fungal Sepsis MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Perforation MetaADEDB
General Physical Health Deterioration MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glutamate Dehydrogenase Increased MetaADEDB
Gout ADReCS
Graft Loss MetaADEDB
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemoglobinuria MetaADEDB
Haemolysis MetaADEDB
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Injury MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Artery Stenosis MetaADEDB
Hepatic Cirrhosis ADReCS
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Failure ADReCS
Hepatic Neoplasm Malignant MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Zoster MetaADEDB
High Blood Pressure MetaADEDB
Hyperamylasaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperparathyroidism MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hyperuricaemia ADReCS
Hypoalbuminaemia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Seizure MetaADEDB
Hypokalaemia ADReCS
Hypotension ADReCS
Hypovolaemia ADReCS
Hypovolaemic Shock MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Impotence ADReCS
Increased Bronchial Secretion MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insomnia ADReCS
Insufficiency Renal SIDER
International Normalised Ratio Increased MetaADEDB
Intoxication SIDER
Ischaemic Cardiomyopathy MetaADEDB
Ischaemic Hepatitis MetaADEDB
Itch MetaADEDB
Kidney Failure MetaADEDB
Kidney Transplant Rejection MetaADEDB
Labile Hypertension MetaADEDB
Left Atrial Dilatation MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukaemoid Reaction MetaADEDB
Leukopenia ADReCS
Linear Iga Disease MetaADEDB
Lip Erosion MetaADEDB
Liver Transplant Rejection MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Lung Cancer Metastatic MetaADEDB
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lyell MetaADEDB
Lymphedema MetaADEDB
Malabsorption MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Metabolic Encephalopathy MetaADEDB
Miosis MetaADEDB
Mouth Pain MetaADEDB
Mouth Ulcer MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Abscess MetaADEDB
Muscle Disorder MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder ADReCS
Myalgia ADReCS
Myelodysplasia MetaADEDB
Nail Hypertrophy MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Necrolysis Epidermal SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neuralgia MetaADEDB
Nikolsky Sign MetaADEDB
Oedema ADReCS
Oesophageal Disorder ADReCS
Oesophageal Haemorrhage ADReCS
Oestrogen Receptor Assay Positive MetaADEDB
Oliguria MetaADEDB
Oral Disorder MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Paraesthesia Oral MetaADEDB
Paraneoplastic Pemphigus MetaADEDB
Pericardial Effusion MetaADEDB
Peripheral Arterial Occlusive Disease MetaADEDB
Peritoneal Dialysis Complication MetaADEDB
Petechia MetaADEDB
Pitting Oedema MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumomediastinum MetaADEDB
Pneumonia Klebsiella MetaADEDB
Poisoning ADReCS
Pollakiuria ADReCS
Portal Hypertension MetaADEDB
Portal Vein Thrombosis MetaADEDB
Primary Hypogonadism MetaADEDB
Prinzmetal Angina MetaADEDB
Progesterone Receptor Assay MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time Abnormal MetaADEDB
Pseudomonas Infection MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Hypertension MetaADEDB
Purulent Discharge MetaADEDB
Qrs Axis Abnormal MetaADEDB
Rash ADReCS
Rectal Haemorrhage ADReCS
Renal Failure ADReCS
Renal Function Test Abnormal MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Atrophy MetaADEDB
Respiratory Failure MetaADEDB
Retinal Vasculitis MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis ADReCS
Right Heart Failure MetaADEDB
Rosai-Dorfman Syndrome MetaADEDB
Rotavirus Test Positive MetaADEDB
Sensitivity Of Teeth MetaADEDB
Septic Shock MetaADEDB
Serratia Bacteraemia MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock ADReCS
Shunt Thrombosis ADReCS
Sinus Bradycardia MetaADEDB
Sjogren Syndrome MetaADEDB
Spinning Sensation MetaADEDB
Spleen Disorder MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stevens-Johnson Syndrome ADReCS
Streptococcal Infection MetaADEDB
Sudden Death MetaADEDB
Supraventricular Tachycardia MetaADEDB
Swollen Tongue MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tarsal Tunnel Syndrome MetaADEDB
Tenderness ADReCS
Tension ADReCS
Therapeutic Agent Toxicity ADReCS
Thirst ADReCS
Throat Sore SIDER
Throat Tightness MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Thrombosis ADReCS
Tonsillar Hypertrophy MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Tracheitis MetaADEDB
Transplant Failure MetaADEDB
Ulcer Haemorrhage MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Limb Fracture MetaADEDB
Urinary Tract Infection Pseudomonal MetaADEDB
Varicose Vein Ruptured MetaADEDB
Vascular Graft MetaADEDB
Vascular Insufficiency MetaADEDB
Vasoconstriction MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Ventricular Tachycardia ADReCS
Vital Capacity Decreased MetaADEDB
Vitamin B 12 Deficiency MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Gain MetaADEDB

InAADR: Drug-Protein-ADRs database