InAADR

Drug Information

Drug Name: Tigecycline (220620-09-7)
PubChem ID: 54686904
SMILES: CC(C)(C)NCC(=O)NC1=C(C2=C(C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C2O)O)O)C(=O)N)N(C)C)C(=C1)N(C)C)O
InchiKey: SOVUOXKZCCAWOJ-HJYUBDRYSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 585.658
LogP: 0.3566
Ring Count: 1
Hydrogen Bond Acceptor Count: 11
Hydrogen Bond Donor Count: 7
Total Polar Surface Area: 205.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Abscess MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Faeces ADReCS
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abscess ADReCS
Abscess Drainage MetaADEDB
Abscess Oral MetaADEDB
Acidosis PROTECT
Acinetobacter Bacteraemia MetaADEDB
Acinetobacter Infection MetaADEDB
Acquired Porphyria MetaADEDB
Activated Partial Thromboplastin Time Abnormal ADReCS
Activated Partial Thromboplastin Time Prolonged ADReCS
Acute Graft Versus Host Disease In Intestine MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Adenoma MetaADEDB
Adrenal Insufficiency MetaADEDB
Alanine Aminotransferase Increased ADReCS
Allergic Dermatitis MetaADEDB
Allergic Reaction ADReCS
Alveolitis MetaADEDB
Amentia MetaADEDB
Amylase Increased SIDER
Anaemia ADReCS
Anaphylactic Reaction PROTECT
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anhedonia MetaADEDB
Anorexia ADReCS
Antibiotic Level Below Therapeutic MetaADEDB
Aortic Calcification MetaADEDB
Aortic Rupture MetaADEDB
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block SIDER
Atrioventricular Block First Degree SIDER
Azotaemia PROTECT
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Cell Carcinoma MetaADEDB
Benign Intracranial Hypertension PROTECT
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dilatation MetaADEDB
Bladder Distension MetaADEDB
Bladder Retention MetaADEDB
Blindness ADReCS
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Abnormal ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased ADReCS
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Culture Positive MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Urea Increased ADReCS
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Disorder MetaADEDB
Bone Operation MetaADEDB
Bradycardia ADReCS
Brain Natriuretic Peptide Increased MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchitis MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Bruise MetaADEDB
Caecum Operation MetaADEDB
Candidiasis ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiogenic Shock MetaADEDB
Cardiomyopathy MetaADEDB
Catheter Related Infection MetaADEDB
Cellulitis MetaADEDB
Cellulitis Gangrenous MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis MetaADEDB
Cholestasis ADReCS
Cholestatic Liver Injury PROTECT
Choroidal Detachment MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Coagulopathy SIDER
Colitis ADReCS
Coma MetaADEDB
Compression Fracture MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Constipation ADReCS
Cor Pulmonale MetaADEDB
Corneal Oedema MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Creatine Phosphokinase Increased SIDER
Creatinine Increased SIDER
Creatinine Renal Clearance Decreased ADReCS
Culture Positive MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytolytic Hepatitis ADReCS
Death ADReCS
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Prosthesis Placement MetaADEDB
Dermatitis ADReCS
Device Related Infection MetaADEDB
Diabetic Foot ADReCS
Diabetic Foot Infection ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diplopia MetaADEDB
Discomfort ADReCS
Disease Progression ADReCS
Diverticulum Oesophageal MetaADEDB
Dizziness ADReCS
Drug Ineffective MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Ecchymoses MetaADEDB
Ecchymosis ADReCS
Ectropion MetaADEDB
Effusion ADReCS
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Abnormal SIDER
Electrocardiogram Qt Prolonged SIDER
Electrocardiogram T Wave Amplitude Decreased MetaADEDB
Emesis MetaADEDB
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
Endodontic Procedure MetaADEDB
Enterococcal Infection MetaADEDB
Enterococcal Sepsis MetaADEDB
Eosinophilia ADReCS
Eosinophilic Myocarditis MetaADEDB
Erb Palsy MetaADEDB
Escherichia Bacteraemia MetaADEDB
Esophageal Stenosis MetaADEDB
Extrapyramidal Disorder MetaADEDB
Extrasystoles ADReCS
Eye Injury MetaADEDB
Face Pain MetaADEDB
Facial Bones Fracture MetaADEDB
Faecal Incontinence ADReCS
Fat Tissue Increased MetaADEDB
Feeling Abnormal ADReCS
Fever Chills SIDER
Flatulence ADReCS
Floaters MetaADEDB
Foot Infection SIDER
Fungaemia MetaADEDB
Fungal Endocarditis MetaADEDB
Fungal Skin Infection ADReCS
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrinoma MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Health Deterioration MetaADEDB
Genital Discharge ADReCS
Glaucoma MetaADEDB
Globulinuria MetaADEDB
Glossitis ADReCS
Granulocytosis MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemolysis ADReCS
Head Injury MetaADEDB
Headache ADReCS
Heart-Lung Transplant Rejection MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Failure ADReCS
Hepatic Trauma MetaADEDB
Hepatitis Acute MetaADEDB
Hepatocellular Injury ADReCS
Hepatosplenomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Hesitancy MetaADEDB
Hiccups ADReCS
High Blood Pressure MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hyperbilirubinaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperphosphataemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypocalcaemia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hyponatraemia ADReCS
Hypophosphataemia ADReCS
Hypoproteinaemia ADReCS
Hypotension ADReCS
Hypotony Of Eye MetaADEDB
Hypovolaemic Shock MetaADEDB
Ill-Defined Disorder ADReCS
Immunosuppressant Drug Level MetaADEDB
Impaired Healing ADReCS
Impingement Syndrome MetaADEDB
Incontinence ADReCS
Increased Bronchial Secretion ADReCS
Infection ADReCS
Inflammation ADReCS
Infusion Site Irritation MetaADEDB
Injection Site Inflammation ADReCS
Injection Site Oedema ADReCS
Injection Site Pain ADReCS
Injection Site Phlebitis ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
International Normalised Ratio Increased ADReCS
Intraocular Lens Implant MetaADEDB
Jaundice ADReCS
Keratitis Sicca MetaADEDB
Kidney Failure MetaADEDB
Kidney Function Abnormal ADReCS
Klebsiella Bacteraemia MetaADEDB
Klebsiella Infection MetaADEDB
Lactic Dehydrogenase Activity Increased SIDER
Left Ventricular Dysfunction MetaADEDB
Leucopenia MetaADEDB
Leukocytosis ADReCS
Leukocyturia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Leukorrhea ADReCS
Liver Function Test Abnormal ADReCS
Liver Injury ADReCS
Local Reaction SIDER
Localised Infection ADReCS
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lyell MetaADEDB
Malaise ADReCS
Malnourished MetaADEDB
Mental Disorder MetaADEDB
Metabolic Encephalopathy MetaADEDB
Methicillin-Resistant Staphylococcal Aureus Infection SIDER
Mouth Bleeding MetaADEDB
Mpd MetaADEDB
Mucosal Inflammation ADReCS
Multi-Organ Failure MetaADEDB
Muscle Twitching ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myopia MetaADEDB
Nausea ADReCS
Nephritis Allergic MetaADEDB
Nephrolithiasis MetaADEDB
Nephropathy Toxic MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neutropenia ADReCS
No Match PROTECT
No Therapeutic Response MetaADEDB
Nodule Skin MetaADEDB
Nosocomial Infection MetaADEDB
Nosocomial Pneumonia SIDER
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Food Impaction MetaADEDB
Oesophageal Obstruction MetaADEDB
Open Reduction Of Fracture MetaADEDB
Opportunistic Infection MetaADEDB
Oral Candidiasis ADReCS
Oral Mucosal Hypertrophy MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis ADReCS
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Pain ADReCS
Palpitations ADReCS
Palsies MetaADEDB
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Pancreatitis Chronic MetaADEDB
Pathogen Resistance MetaADEDB
Periarthritis MetaADEDB
Periodontal Disease MetaADEDB
Peritoneal Effusion MetaADEDB
Peritonitis ADReCS
Pharyngitis ADReCS
Phlebitis ADReCS
Phosphatase Alkaline Increased SIDER
Photosensitivity Reaction PROTECT
Platelet Count MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pleural Fibrosis MetaADEDB
Pneumonia ADReCS
Pneumonia Klebsiella MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Polyuria ADReCS
Postoperative Wound Infection MetaADEDB
Proctalgia MetaADEDB
Prolapse Repair MetaADEDB
Protein Total Decreased MetaADEDB
Proteus Infection MetaADEDB
Prothrombin Level Decreased ADReCS
Prothrombin Level Increased ADReCS
Prothrombin Time Prolonged ADReCS
Prothrombin Time Shortened ADReCS
Prurigo ADReCS
Pruritus ADReCS
Pseudomembranous Colitis ADReCS
Pseudomonal Bacteraemia MetaADEDB
Pseudomonal Sepsis MetaADEDB
Pseudomonas Infection MetaADEDB
Ptt Prolonged SIDER
Pulmonary Mass MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Rectal Prolapse MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Renal Impairment ADReCS
Renal Tubular Acidosis MetaADEDB
Renal Tubular Disorder MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Retinopathy Hypertensive MetaADEDB
Rib Fracture MetaADEDB
Right Ventricular Dysfunction MetaADEDB
Scoliosis MetaADEDB
Scrotal Oedema ADReCS
Sepsis ADReCS
Sepsis Syndrome MetaADEDB
Septic Shock ADReCS
Serratia Infection MetaADEDB
Shock ADReCS
Shock Haemorrhagic MetaADEDB
Sinus Bradycardia ADReCS
Sinus Tachycardia ADReCS
Skin Discolouration ADReCS
Skin Neoplasm Excision MetaADEDB
Skin Reaction PROTECT
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Spinal Compression Fracture MetaADEDB
Sputum Increased ADReCS
Staphylococcal Infection SIDER
Stenotrophomonas Infection MetaADEDB
Stevens-Johnson Syndrome PROTECT
Streptococcal Bacteraemia MetaADEDB
Supraventricular Tachycardia MetaADEDB
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tendinitis MetaADEDB
Tension ADReCS
Thrombocytopenia ADReCS
Thrombocytosis ADReCS
Thrombophlebitis ADReCS
Tongue Discolouration MetaADEDB
Tooth Discolouration PROTECT
Tooth Extraction MetaADEDB
Tracheal Stenosis MetaADEDB
Transaminases Increased MetaADEDB
Tremor ADReCS
Ulcer Haemorrhage MetaADEDB
Urinary Tract Infection ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Vaginal Cellulitis MetaADEDB
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vaginal Moniliasis SIDER
Vasodilation SIDER
Vasodilation Procedure ADReCS
Ventricular Arrhythmia ADReCS
Ventricular Extrasystoles ADReCS
Vertigo ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vitreous Detachment MetaADEDB
Vitreous Haemorrhage MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Disorder ADReCS
Vulvovaginal Mycotic Infection ADReCS
Vulvovaginitis ADReCS
Wound Infection ADReCS
Wound Infection Fungal MetaADEDB

InAADR: Drug-Protein-ADRs database