InAADR

Drug Information

Drug Name: Tibolone (5630-53-5)
PubChem ID: 444008
SMILES: C[C@@H]1CC2=C(CCC(=O)C2)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O
InchiKey: WZDGZWOAQTVYBX-XOINTXKNSA-N
Therapeutic Category: Anabolic Agents, Androgen Antagonists, Antihypertensive Agents, Antineoplastic Agents, Cardiovascular Agents, Estrogen Receptor Modulators, Hormone Antagonists, Hormones

Computed Drug Properties

Molecular Weight (dalton): 312.453
LogP: 3.8826
Ring Count: 0
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 37.3

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Accelerated Hypertension MetaADEDB
Ageusia MetaADEDB
Alanine Aminotransferase MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia MetaADEDB
Alveolitis Fibrosing MetaADEDB
Amnesia MetaADEDB
Anaesthesia MetaADEDB
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Aptyalism MetaADEDB
Arterial Catheterisation MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthma Late Onset MetaADEDB
Asthmatic Crisis MetaADEDB
Balance Disorder MetaADEDB
Benign Breast Neoplasm MetaADEDB
Bile Duct Obstruction MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood In Urine MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Pain MetaADEDB
Bronchopneumonia MetaADEDB
Burn Oesophageal MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Vagina MetaADEDB
Carcinoma Of The Colon MetaADEDB
Catheter Related Infection MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerebral Venous Thrombosis MetaADEDB
Cervix Carcinoma Stage Ii MetaADEDB
Cholangiolitis MetaADEDB
Chromaturia MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cold Extremities MetaADEDB
Confabulation MetaADEDB
Coombs Positive Haemolytic Anaemia MetaADEDB
Deafness Unilateral MetaADEDB
Decreased Immune Responsiveness MetaADEDB
Demyelination MetaADEDB
Dengue Fever MetaADEDB
Depressed Mood MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulitis MetaADEDB
Dizziness MetaADEDB
Dizziness Exertional MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dysgeusia MetaADEDB
Dyspnea Exertional MetaADEDB
Dysstasia MetaADEDB
Ear Pruritus MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Emesis MetaADEDB
Endometriosis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Excessive Salivation MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Swelling MetaADEDB
Fatigue MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Feeling Of Despair MetaADEDB
Femur Fracture MetaADEDB
Flooding MetaADEDB
Formication MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Bleed MetaADEDB
Globulinuria MetaADEDB
Hair Colour Changes MetaADEDB
Heart Rate Increased MetaADEDB
Hepatitis MetaADEDB
Hepatocellular Damage MetaADEDB
Herpes Zoster MetaADEDB
Hypoaesthesia Facial MetaADEDB
Hypophagia MetaADEDB
Hypoxia MetaADEDB
Iatrogenic Injury MetaADEDB
Illusion MetaADEDB
Increased Platelet Count MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Intestinal Perforation MetaADEDB
Iron Binding Capacity Total Increased MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Itch MetaADEDB
Lethargy MetaADEDB
Loss Of Weight MetaADEDB
Lower Limb Fracture MetaADEDB
Macular Oedema MetaADEDB
Malnourished MetaADEDB
Medical Device Complication MetaADEDB
Meniere Disease MetaADEDB
Menometrorrhagia MetaADEDB
Micturition Frequency Decreased MetaADEDB
Mouth Pain MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Swelling MetaADEDB
Myocarditis Rheumatic MetaADEDB
Nausea MetaADEDB
Nightmare MetaADEDB
Obsessive Thoughts MetaADEDB
Ocular Vascular Disorder MetaADEDB
Off Label Use MetaADEDB
Oropharyngeal Pain MetaADEDB
Ossicle Disorder MetaADEDB
Ovarian Cyst MetaADEDB
Ovarian Epithelial Cancer MetaADEDB
Pain MetaADEDB
Pain In Throat MetaADEDB
Pericardial Effusion MetaADEDB
Pericarditis Infective MetaADEDB
Persecutory Delusion MetaADEDB
Phaeochromocytoma MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phobia MetaADEDB
Porphyria Non-Acute MetaADEDB
Post Procedural Pain MetaADEDB
Pseudoporphyria MetaADEDB
Salpingitis MetaADEDB
Schizophreniform Disorder MetaADEDB
Sensation Of Heaviness MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Arthritis Staphylococcal MetaADEDB
Serum Ferritin Increased MetaADEDB
Sinus Disorder MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Sleep Apnea MetaADEDB
Sleep-Related Eating Disorder MetaADEDB
Speech Disorder MetaADEDB
Spinning Sensation MetaADEDB
Staphylococcal Infection MetaADEDB
Staphylococcal Osteomyelitis MetaADEDB
Superior Sagittal Sinus Thrombosis MetaADEDB
Swollen Tongue MetaADEDB
Tearfulness MetaADEDB
Thyroid Cancer MetaADEDB
Tinea Pedis MetaADEDB
Tympanosclerosis MetaADEDB
Ulna Fracture MetaADEDB
Upper Limb Fracture MetaADEDB
Urinary Casts MetaADEDB
Urticaria Generalised MetaADEDB
Vaginal Polyp MetaADEDB
Varicose Vein MetaADEDB
Viral Myocarditis MetaADEDB
Visual Disturbance MetaADEDB
Weight Gain MetaADEDB
Wheeze MetaADEDB
Withdrawal Syndrome MetaADEDB
Wound Infection MetaADEDB

InAADR: Drug-Protein-ADRs database