InAADR

Drug Information

Drug Name: Rosiglitazone (122320-73-4)
PubChem ID: 77999
SMILES: CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
InchiKey: YASAKCUCGLMORW-UHFFFAOYSA-N
Therapeutic Category: Hypoglycemic Agents

Computed Drug Properties

Molecular Weight (dalton): 357.435
LogP: 2.4909
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 71.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abnormal Vision MetaADEDB
Accidental Overdose MetaADEDB
Accommodation Disorder MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Myocardial Infarction MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Adrenal Suppression MetaADEDB
Adverse Event MetaADEDB
Afib MetaADEDB
Alanine Aminotransferase Increased ADReCS
Anaemia ADReCS
Anaemia Of Chronic Disease MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angina MetaADEDB
Angina Unstable MetaADEDB
Angioedema ADReCS
Angiopathy MetaADEDB
Anhedonia MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anxiety MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Stenosis MetaADEDB
Aortic Valve Sclerosis MetaADEDB
Apoplexy MetaADEDB
Apparent Death MetaADEDB
Appendix Disorder MetaADEDB
Arrhythmia MetaADEDB
Arterial Bypass Operation MetaADEDB
Arterial Disorder MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Stenosis MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Malformation MetaADEDB
Arthralgia ADReCS
Asthenia ADReCS
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block Complete MetaADEDB
Autoimmune Disorder MetaADEDB
Back Pain ADReCS
Bacterial Vaginitis MetaADEDB
Biopsy Bone Marrow Abnormal MetaADEDB
Birth Defect MetaADEDB
Blindness Unilateral MetaADEDB
Blood Arsenic Increased MetaADEDB
Blood Creatine Phosphokinase Mm Increased MetaADEDB
Blood Disorder MetaADEDB
Blood Glucose Decreased ADReCS
Blood Urea Increased ADReCS
Bone Debridement MetaADEDB
Bone Fracture MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Brain Damage MetaADEDB
Brain Oedema MetaADEDB
Bronchiectasis MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Left MetaADEDB
Burkitt Lymphoma MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Chronic MetaADEDB
Cardiac Failure Congestive ADReCS
Cardiac Hypertrophy MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Operation MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardiac Septal Defect MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Above Therapeutic MetaADEDB
Cardiomyopathy MetaADEDB
Cardiovascular Disorder MetaADEDB
Carotid Arteriosclerosis MetaADEDB
Carotid Artery Disease MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Artery Thrombosis MetaADEDB
Cerebral Thrombosis MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervical Discharge MetaADEDB
Chest Pain MetaADEDB
Choking Sensation MetaADEDB
Cholecystectomies MetaADEDB
Chondritis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cirrhosis MetaADEDB
Closed Head Injury MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Constipation ADReCS
Contusion ADReCS
Coronary Artery Bypass MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Artery Stenosis MetaADEDB
Coronary Artery Thrombosis MetaADEDB
Cough ADReCS
Csf Protein MetaADEDB
Cystocele MetaADEDB
Death MetaADEDB
Decreased Activity MetaADEDB
Delusion MetaADEDB
Demyelination MetaADEDB
Dental Discomfort MetaADEDB
Dental Operation MetaADEDB
Dental Prosthesis Placement MetaADEDB
Denture Wearer MetaADEDB
Depression ADReCS
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Diabetic Macular Edema SIDER
Diabetic Retinal Oedema ADReCS
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Diverticulum Intestinal Haemorrhagic MetaADEDB
Dizziness ADReCS
Dizziness Postural ADReCS
Drop Attacks MetaADEDB
Dry Mouth ADReCS
Dysaesthesia ADReCS
Dyskinesia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphasia MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea Exacerbated MetaADEDB
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Easy Bruisability MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Effusion ADReCS
Ejection Fraction Decreased MetaADEDB
Embolic Stroke MetaADEDB
Emotional Disorder MetaADEDB
Emotional Distress MetaADEDB
Endotracheal Intubation MetaADEDB
Erythema ADReCS
Erythrosis MetaADEDB
Eye Laser Surgery MetaADEDB
Eyeball Avulsion MetaADEDB
Faecal Incontinence MetaADEDB
Faeces Pale MetaADEDB
Failure To Thrive MetaADEDB
Fatigue ADReCS
Femoral Neck Fracture MetaADEDB
Fibroma MetaADEDB
Fistula Repair MetaADEDB
Flatulence MetaADEDB
Fluid Overload MetaADEDB
Foot Fracture MetaADEDB
Forced Expiratory Volume Decreased MetaADEDB
Gallop Rhythm Present MetaADEDB
Gastric Ileus MetaADEDB
Gastric Lavage MetaADEDB
Gastrointestinal Pain ADReCS
Gingival Infection MetaADEDB
Glycosylated Haemoglobin MetaADEDB
Granulomatous Liver Disease MetaADEDB
Haematocrit Decreased ADReCS
Haemoglobin Decreased ADReCS
Hair Texture Abnormal MetaADEDB
Hallucination ADReCS
Hallucinations Mixed MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Injury MetaADEDB
Heart Valve Replacement MetaADEDB
Hemiplegia MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Necrosis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatocellular Damage MetaADEDB
Hiccups ADReCS
High Blood Pressure MetaADEDB
Hilar Lymphadenopathy MetaADEDB
Histoplasmosis MetaADEDB
Hot Flush ADReCS
Hydronephrosis MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperbilirubinaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypertension ADReCS
Hypertensive Emergency MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypoglycaemia ADReCS
Ill-Defined Disorder MetaADEDB
Immobile MetaADEDB
Impaired Work Ability MetaADEDB
Implantable Defibrillator Insertion MetaADEDB
Incision Site Abscess MetaADEDB
Incision Site Pain MetaADEDB
Increased Appetite ADReCS
Infarction ADReCS
Influenza ADReCS
Injection Site Ulcer MetaADEDB
Injury ADReCS
Insomnia ADReCS
Intestinal Haemorrhage MetaADEDB
Intracardiac Thrombus MetaADEDB
Intracranial Hypotension MetaADEDB
Intraocular Inflammation MetaADEDB
Ischaemia ADReCS
Ischaemic Cardiomyopathy MetaADEDB
Ischaemic Hepatitis MetaADEDB
Ischaemic Stroke MetaADEDB
Jaw Fracture MetaADEDB
Joint Injury MetaADEDB
Judgement Impaired MetaADEDB
Jugular Vein Distension MetaADEDB
Ketonuria ADReCS
Kidney Failure MetaADEDB
Laryngospasm MetaADEDB
Left Atrial Dilatation MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leg Amputation MetaADEDB
Lethargy ADReCS
Life Expectancy Shortened MetaADEDB
Lipids Abnormal ADReCS
Loss Of Employment MetaADEDB
Lung Edema MetaADEDB
Lymphocytosis MetaADEDB
Macular Oedema ADReCS
Macular Pseudohole MetaADEDB
Maculopathy MetaADEDB
Malignant Hypertension MetaADEDB
Mallory-Weiss Syndrome MetaADEDB
Mental Disorder MetaADEDB
Mitral Valve Disease MetaADEDB
Mitral Valve Prolapse MetaADEDB
Multiple Fractures MetaADEDB
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Fatigue MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder MetaADEDB
Musculoskeletal Pain ADReCS
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Nasal Congestion ADReCS
Nasopharyngeal Disorder MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Night Blindness MetaADEDB
Night Cramps MetaADEDB
Nightmare ADReCS
Non-Cardiac Chest Pain MetaADEDB
Obstruction MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oropharyngeal Pain ADReCS
Orthopnea MetaADEDB
Osteogenesis Imperfecta MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Palpitation MetaADEDB
Palsies MetaADEDB
Panniculitis MetaADEDB
Paraesthesia ADReCS
Partner Stress MetaADEDB
Pedal Pulse Absent MetaADEDB
Pericardial Effusion MetaADEDB
Periodontal Disease MetaADEDB
Periorbital Oedema ADReCS
Peripartum Cardiomyopathy MetaADEDB
Pharyngolaryngeal Pain SIDER
Phlebothrombosis MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pleural Fibrosis MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Prinzmetal Angina MetaADEDB
Prostatic Disorder MetaADEDB
Proteus Infection MetaADEDB
Pruritus ADReCS
Pulmonary Arterial Hypertension MetaADEDB
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Thrombosis MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Quality Of Life Decreased MetaADEDB
Rales MetaADEDB
Rash ADReCS
Rectal Fistula Repair MetaADEDB
Reflux Gastritis MetaADEDB
Renal Injury MetaADEDB
Renal Surgery MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Retinitis MetaADEDB
Rubella MetaADEDB
Scrotal Infection MetaADEDB
Self Mutilation MetaADEDB
Sepsis Syndrome MetaADEDB
Serum Ferritin Decreased ADReCS
Silent Myocardial Infarction MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Congestion ADReCS
Sinusitis ADReCS
Sleep Apnea MetaADEDB
Social Avoidant Behaviour ADReCS
Somnolence ADReCS
Spondylolysis MetaADEDB
Stent Placement MetaADEDB
Stevens-Johnson Syndrome ADReCS
Subcutaneous Abscess MetaADEDB
Sudden Cardiac Death MetaADEDB
Superior Sagittal Sinus Thrombosis MetaADEDB
Supraventricular Tachycardia MetaADEDB
Tachycardia Ventricular MetaADEDB
Thrombosis In Device MetaADEDB
Tobacco Abuse MetaADEDB
Tongue Haematoma MetaADEDB
Tooth Loss MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Twin Pregnancy MetaADEDB
Unevaluable Event MetaADEDB
Unintended Pregnancy MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urticaria ADReCS
Vascular Graft MetaADEDB
Vascular Injury MetaADEDB
Ventricular Dyskinesia MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vertebrobasilar Insufficiency MetaADEDB
Viral Upper Respiratory Tract Infection MetaADEDB
Visual Acuity Reduced ADReCS
Vitamin B 12 Deficiency MetaADEDB
Vocal Cord Paralysis MetaADEDB
Volume Blood Increased ADReCS
Volume Plasma Increased SIDER
Vomiting ADReCS
Vulvovaginal Candidiasis MetaADEDB
Weight Gain MetaADEDB
Weight Increased ADReCS
Withdrawal Of Life Support MetaADEDB
Withdrawn SIDER
Wrist Fracture MetaADEDB
Yawning MetaADEDB

InAADR: Drug-Protein-ADRs database