InAADR

Drug Information

Drug Name: Propylthiouracil (51-52-5)
PubChem ID: 657298
SMILES: CCCC1=CC(=O)NC(=S)N1
InchiKey: KNAHARQHSZJURB-UHFFFAOYSA-N
Therapeutic Category: Antimetabolites, Antithyroid Agents, Hormone Antagonists, Hormones, Noxae

Computed Drug Properties

Molecular Weight (dalton): 170.237
LogP: 1.38499
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 48.65

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Vasculitis anti-neutrophil cytoplasmic antibody (ANCA) (P00002) Propylthiouracil-induced vasculitis associated with anti-neutrophil cytoplasmic antibody (ANCA) [ ADR Type 5 ] Case of propylthiouracil-induced vasculitis associated with anti-neutrophil cytoplasmic antibody (ANCA); review of literature

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Ecg MetaADEDB
Accident MetaADEDB
Accidental Exposure MetaADEDB
Aching Joints MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Myocardial Infarction MetaADEDB
Afib MetaADEDB
Ageusia ADReCS
Agranulocytosis ADReCS
Allergic Dermatitis MetaADEDB
Allergic Vasculitis MetaADEDB
Alopecia ADReCS
Anaemia ADReCS
Anemia MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Anorexia MetaADEDB
Anoxia MetaADEDB
Anti-Neutrophil Cytoplasmic Antibody Positive Vasculitis MetaADEDB
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis MetaADEDB
Anti-Thyroid Antibody Positive MetaADEDB
Antineutrophil Cytoplasmic Antibody Positive MetaADEDB
Antinuclear Antibody MetaADEDB
Antiphospholipid Syndrome MetaADEDB
Anuria MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Regurgitation MetaADEDB
Aortic Stenosis MetaADEDB
Aphthous Stomatitis MetaADEDB
Aplastic Anaemia ADReCS
Arrhythmia MetaADEDB
Arteriosclerosis MetaADEDB
Arteritis ADReCS
Arthralgia ADReCS
Arthritis MetaADEDB
Asthenia MetaADEDB
Asystole MetaADEDB
Atherosclerosis MetaADEDB
Atrial Flutter MetaADEDB
Atrial Hypertrophy MetaADEDB
Atrial Septal Defect MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Autoimmune Hepatitis MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Biopsy Skin MetaADEDB
Bladder Distension MetaADEDB
Blister MetaADEDB
Blood 25-Hydroxycholecalciferol Decreased MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Coagulation Disorders MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Blurred Vision MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Diseases MetaADEDB
Bone Marrow Failure ADReCS
Breech Presentation MetaADEDB
Caesarean Section MetaADEDB
Candida Infection MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiovascular Abnormalities MetaADEDB
Catalepsy MetaADEDB
Cerebral Hemorrhage MetaADEDB
Cholecystitis MetaADEDB
Cholestasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Choluria MetaADEDB
Cirrhosis MetaADEDB
Clostridial Infection MetaADEDB
Clubbing MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat MetaADEDB
Colitis Ischaemic MetaADEDB
Congenital Genital Malformation Female MetaADEDB
Congenital Heart Disease MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Conjunctival Disorder MetaADEDB
Conjunctivitis Infective MetaADEDB
Coombs Positive Haemolytic Anaemia MetaADEDB
Coronary Artery Thrombosis MetaADEDB
Coughing Blood MetaADEDB
Crackles Lung MetaADEDB
Cryoglobulinemia MetaADEDB
Cytopenia SIDER
Dandy-Walker Syndrome MetaADEDB
Death ADReCS
Deep Vein Thromboses MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Diarrhea MetaADEDB
Diastolic Dysfunction MetaADEDB
Dilatation Atrial MetaADEDB
Diplopia MetaADEDB
Disorder Of Globe MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness MetaADEDB
Drowsiness SIDER
Drug Dispensing Error MetaADEDB
Drug Exposure Before Pregnancy MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Fever ADReCS
Drug Hypersensitivity MetaADEDB
Drug Tolerance MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnea MetaADEDB
Dysstasia MetaADEDB
Ear Ache MetaADEDB
Echocardiogram Abnormal MetaADEDB
Edema MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism MetaADEDB
Epigastric Distress SIDER
Epistaxis MetaADEDB
Erectile Dysfunction MetaADEDB
Erythema ADReCS
Erythema Nodosum ADReCS
Erythropenia MetaADEDB
Euthyroid Sick Syndromes MetaADEDB
Exanthema MetaADEDB
Exophthalmos MetaADEDB
Fallot Tetralogy MetaADEDB
Fatigue MetaADEDB
Fever MetaADEDB
Foetal Disorder MetaADEDB
Foetal Haemoglobin Decreased MetaADEDB
Gallbladder Polyp MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gingival Hemorrhage MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis ADReCS
Glomerulonephritis Iga MetaADEDB
Glomerulonephritis Membranous MetaADEDB
Glomerulonephritis Rapidly Progressive ADReCS
Glomerulosclerosis Focal Segmental MetaADEDB
Goiter MetaADEDB
Goiter Nodular MetaADEDB
Granulocytopenia ADReCS
Granuloma MetaADEDB
Graves Disease MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemothorax MetaADEDB
Headache ADReCS
Hearing Loss Bilateral MetaADEDB
Hearing Loss Sensorineural MetaADEDB
Heart Rate Increased MetaADEDB
Hematuria MetaADEDB
Hemoptysis MetaADEDB
Hemorrhage MetaADEDB
Hepatic Encephalopathy MetaADEDB
Hepatic Failure ADReCS
Hepatic Necrosis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis Chronic MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Virus Infection MetaADEDB
Hydrops Foetalis MetaADEDB
Hypergammaglobulinemia MetaADEDB
Hyperhidrosis MetaADEDB
Hypertension MetaADEDB
Hyperthyroidism MetaADEDB
Hypoprothrombinaemia ADReCS
Hypothyroidism MetaADEDB
Ild MetaADEDB
Immune Complex Diseases MetaADEDB
Increased Platelet Count MetaADEDB
Infant Newborn Diseases MetaADEDB
Infection Upper Respiratory MetaADEDB
Inflammation MetaADEDB
Injection Site Erythema MetaADEDB
Intention Tremor MetaADEDB
Interstitial Lung Disease ADReCS
Interstitial Pneumonia SIDER
Intestinal Diseases MetaADEDB
Ischemia MetaADEDB
Iucd Complication MetaADEDB
Jaundice ADReCS
Jaundice Obstructive MetaADEDB
Kidney Failure Chronic MetaADEDB
Kidney Tubular Necrosis Acute MetaADEDB
Laryngeal Ulceration MetaADEDB
Leukocytoclastic Vasculitis ADReCS
Leukocytosis MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Liver Diseases Alcoholic MetaADEDB
Liver Failure MetaADEDB
Liver Failure Acute MetaADEDB
Liver Transplant MetaADEDB
Loss Of Weight MetaADEDB
Lung Diseases MetaADEDB
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration ADReCS
Lung Neoplasms MetaADEDB
Lupus Erythematosus SIDER
Lupus Erythematosus Systemic MetaADEDB
Lupus Nephritis MetaADEDB
Lupus-Like Syndrome ADReCS
Lyell MetaADEDB
Lymphadenopathy ADReCS
Lymphatic Diseases MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Maternal Use Of Illicit Drugs MetaADEDB
Meningitis MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Occlusion MetaADEDB
Mesenteric Vascular Disease MetaADEDB
Metabolic Encephalopathy MetaADEDB
Microscopic Polyangiitis MetaADEDB
Middle Insomnia MetaADEDB
Mitral Valve Prolapse MetaADEDB
Mucormycosis MetaADEDB
Mucosal Dryness MetaADEDB
Multiple Pulmonary Nodules MetaADEDB
Multiple Sclerosis MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myocarditis MetaADEDB
Myositis MetaADEDB
Nausea ADReCS
Necrosis MetaADEDB
Neonatal Tachycardia MetaADEDB
Nephritis ADReCS
Nephritis Interstitial MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Neutropenia MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nose Diseases MetaADEDB
Ocular Icterus MetaADEDB
Oedema ADReCS
Opportunistic Infection MetaADEDB
Oral Disorder MetaADEDB
Oral Polypectomy MetaADEDB
Oral Ulcer MetaADEDB
Pain Pelvic MetaADEDB
Pallor MetaADEDB
Pancytopenia ADReCS
Paraesthesia ADReCS
Paranoia MetaADEDB
Patent Ductus Arteriosis MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Haemorrhage MetaADEDB
Pericarditis MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Pigmentation SIDER
Pigmentation Disorder ADReCS
Pigmentation Skin SIDER
Platelet Count MetaADEDB
Pneumonia ADReCS
Post Procedural Infection MetaADEDB
Precancerous Conditions MetaADEDB
Premature Baby MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Procedural Complication MetaADEDB
Procedural Pain MetaADEDB
Proctalgia MetaADEDB
Proteinuria MetaADEDB
Pruritus ADReCS
Psychoses MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Artery Stenosis MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Purpura MetaADEDB
Purpura Schoenlein-Henoch MetaADEDB
Purulence MetaADEDB
Pyelectasia MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Reflex Abnormal MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Insufficiency MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Right Ventricular Hypertrophy MetaADEDB
Salivary Gland Disorder ADReCS
Scleritis MetaADEDB
Seizures MetaADEDB
Septic Shock MetaADEDB
Serositis MetaADEDB
Sexual Dysfunctions Psychological MetaADEDB
Sinus Bradycardia MetaADEDB
Sinus Headache MetaADEDB
Skin Discolouration ADReCS
Skin Lesion MetaADEDB
Skin Pigmentation ADReCS
Skin Turgor Decreased MetaADEDB
Skin Ulcer ADReCS
Somnolence ADReCS
Splenomegaly ADReCS
Stevens-Johnson Syndrome MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Synovitis MetaADEDB
Systemic Lupus Erythematosus ADReCS
Systemic Vasculitis MetaADEDB
Thrombocytopenia ADReCS
Thrombosis MetaADEDB
Thyroid Neoplasms MetaADEDB
Thyrotoxicosis MetaADEDB
Tinnitus MetaADEDB
Tri-Iodothyronine Increased MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Urogenital Fistula MetaADEDB
Urticaria ADReCS
Uterine Pain MetaADEDB
Uterine Rupture MetaADEDB
Vasculitis ADReCS
Vasculitis Central Nervous System MetaADEDB
Vasculitis Leukocytoclastic Cutaneous MetaADEDB
Vertigo ADReCS
Vomiting ADReCS
Wegener Granulomatosis MetaADEDB
Weight Fluctuation MetaADEDB
Weight Loss MetaADEDB

InAADR: Drug-Protein-ADRs database