InAADR

Drug Information

Drug Name: Pristinamycin (11006-76-1)
PubChem ID: 11979535
SMILES: CCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CCC(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.CC1C=CC(=O)NCC=CC(=CC(CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)OC1C(C)C)O)C
InchiKey: MVTQIFVKRXBCHS-FHWPYUEJSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents, Enzyme Inhibitors, Protein Synthesis Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 1349.5
LogP: 3.8634
Ring Count: 4
Hydrogen Bond Acceptor Count: 19
Hydrogen Bond Donor Count: 6
Total Polar Surface Area: 363.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Methotrexate (59-05-2) Anus Abnormal Synergistic Not understood Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic
Methotrexate (59-05-2) Balanitis Synergistic Not understood Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic
Methotrexate (59-05-2) Mucositis Oral Synergistic Not understood Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic
Methotrexate (59-05-2) Neutropenia Synergistic Not understood Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic
Methotrexate (59-05-2) Thrombocytopenia Synergistic Not understood Severe Interaction Between Methotrexate and a Macrolide-Like Antibiotic

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Adenopathy MetaADEDB
Ageusia MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Angioedema MetaADEDB
Aspiration Bone Marrow MetaADEDB
Bacteraemia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bone Inflammation MetaADEDB
Bone Marrow Failure MetaADEDB
Bronchitis MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cell Death MetaADEDB
Cheilitis MetaADEDB
Conjunctival Deposit MetaADEDB
Craniotomy MetaADEDB
Csf Culture Positive MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cutaneous Vasculitis MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Drug Intolerance MetaADEDB
Drug Resistance MetaADEDB
Eosinophil Count Increased MetaADEDB
Erysipelas MetaADEDB
Erythrodermic Psoriasis MetaADEDB
Generalised Erythema MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hyperventilation MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Lactobacillus Infection MetaADEDB
Meningitides MetaADEDB
Mouth Bleeding MetaADEDB
Multiple-Drug Resistance MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Protein Total Increased MetaADEDB
Pustular Psoriasis MetaADEDB
Rhonchi MetaADEDB
Skin Plaque MetaADEDB
Staphylococcal Infection MetaADEDB
Staphylococcal Infections MetaADEDB
Thrombophlebitis MetaADEDB
Toxic Skin Eruption MetaADEDB
Treatment Failure MetaADEDB
Vaginal Contraceptive Device Expelled MetaADEDB

InAADR: Drug-Protein-ADRs database