InAADR

Drug Information

Drug Name: Pirenzepine (28797-61-7)
PubChem ID: 4848
SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4
InchiKey: RMHMFHUVIITRHF-UHFFFAOYSA-N
Therapeutic Category: Anti-Ulcer Agents, Cholinergic Agents, Cholinergic Antagonists, Gastrointestinal Agents, Muscarinic Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 351.41
LogP: 1.5594
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 68.78

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Impair Working Memory Muscarinic acetylcholine receptor M1 (P11229) Blockade of hippocampal M2 muscarinic receptors impairs working memory performance of rats [ ADR Type 1 ] Blockade of hippocampal M1 muscarinic receptors impairs working memory performance of rats

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abnormal Ecg MetaADEDB
Abnormal Eeg MetaADEDB
Acute Abdomen MetaADEDB
Adynamic Ileus MetaADEDB
Alanine Aminotransferase MetaADEDB
Alcohol Consumption MetaADEDB
Alopecia MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Ankylosing Spondylitis MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Arthritis Rheumatoid MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Ataxia MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrioventricular Block MetaADEDB
Bacterial Toxaemia MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood Sodium MetaADEDB
Body Mass Index Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Bradycardia MetaADEDB
Brain Hypoxia MetaADEDB
Burn Oesophageal MetaADEDB
Calcinosis MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardiogenic Shock MetaADEDB
Catalepsy MetaADEDB
Cellulitis MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Cmv Infection MetaADEDB
Colitis Ischaemic MetaADEDB
Colonic Fistula MetaADEDB
Condition Aggravated MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyanosis MetaADEDB
Diabetic Hyperglycaemic Coma MetaADEDB
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Drowsiness MetaADEDB
Drug Interaction MetaADEDB
Duodenal Ulcer MetaADEDB
Dysgraphia MetaADEDB
Edema Extremities MetaADEDB
Enlarged Spleen MetaADEDB
Epilepsy MetaADEDB
Faecal Incontinence MetaADEDB
Flatulence MetaADEDB
Fractured Pelvis Nos MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Motility Disorder MetaADEDB
Globulinuria MetaADEDB
Glucose Urine MetaADEDB
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haemoglobin Increased MetaADEDB
Hallucinations Mixed MetaADEDB
Heart Attack MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Failure MetaADEDB
Hepatitis C MetaADEDB
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
Hypertension MetaADEDB
Hypokalaemia MetaADEDB
Hypothyroid MetaADEDB
Hypoxia MetaADEDB
Incisional Hernia MetaADEDB
Incontinence MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Influenza Like Illness MetaADEDB
Intervertebral Disc Operation MetaADEDB
Laryngospasm MetaADEDB
Leukopenia Neonatal MetaADEDB
Limb Injury MetaADEDB
Lower Limb Fracture MetaADEDB
Lymph Node Palpable MetaADEDB
Lymphocyte Count Abnormal MetaADEDB
Mallory-Weiss Syndrome MetaADEDB
Memory Disorders MetaADEDB
Metastases To Lung MetaADEDB
Mood Altered MetaADEDB
Multiple System Atrophy MetaADEDB
Muscle Rigidity MetaADEDB
Myopia MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Oculogyration MetaADEDB
Osteomyelitis MetaADEDB
Overdose MetaADEDB
Overweight MetaADEDB
Pallor MetaADEDB
Parotid Gland Enlargement MetaADEDB
Parotitis MetaADEDB
Peptic Ulcer MetaADEDB
Pericardial Effusion MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Fistula MetaADEDB
Postoperative Ileus MetaADEDB
Reflux Esophagitis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Resuscitation MetaADEDB
Seizures MetaADEDB
Seroma MetaADEDB
Shock Haemorrhagic MetaADEDB
Sleep Apnea MetaADEDB
Spinal Disorder MetaADEDB
Spinal Operation MetaADEDB
Spleen Congestion MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stomach Ulcer MetaADEDB
Stress MetaADEDB
Subileus MetaADEDB
Surgery MetaADEDB
Tracheostomy MetaADEDB
Tremor MetaADEDB
Ultrasound Scan Abnormal MetaADEDB
Umbilical Hernia MetaADEDB
White Blood Cell Count Abnormal MetaADEDB
Wound Infection MetaADEDB
X-Ray Gastrointestinal Tract Abnormal MetaADEDB

InAADR: Drug-Protein-ADRs database